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Author Spotlight: Advancing the Analysis of Plasma Extracellular Vesicle Proteome for Cardiovascular Biomarker Studies
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Prospects of plasmapheresis for patients with severe COVID-19

Ilmira R Gilmutdinova1, Maksim Yu Yakovlev1, Petr S Eremin1

  • 1Federal State Budgetary Institution "National Medical Research Centre for Rehabilitation and Balneology" of the Ministry of Health of Russia, Moscow, Russia.

European Journal of Translational Myology
|October 29, 2020
PubMed

Insights

Extracorporeal hemocorrection may help manage severe COVID-19 complications like cytokine storms. This method aims to normalize cytokine levels and reduce organ damage in patients with Coronavirus disease 2019 (COVID-19).

Area of Science:

  • Medical Science
  • Virology
  • Critical Care Medicine

Background:

  • Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, can lead to severe complications.
  • Hypercytokinaemia, or cytokine storm, is a key factor in severe COVID-19, causing acute respiratory distress syndrome (ARDS), respiratory failure, and death.

Purpose of the Study:

  • To evaluate the potential of extracorporeal hemocorrection in managing severe COVID-19.
  • To explore the normalization of cytokine levels and reduction of organ damage using these methods.

Main Methods:

  • Literature analysis of existing studies on extracorporeal methods in COVID-19 patients.
  • Review of clinical practices and their outcomes.

Main Results:

  • Emerging data suggests extracorporeal hemocorrection is a logical approach for normalizing cytokine levels.
  • Positive clinical experience with extracorporeal methods in COVID-19 patients has been reported globally.

Conclusions:

  • Extracorporeal hemocorrection shows promise in mitigating severe complications of COVID-19.
  • Further research and application of these methods could improve patient outcomes in critical cases.

Keywords:
COVID-19coronavirusextracorporeal haemocorrectionplasmapheresis

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