Correlation Between Psoriasis Severity and Nonalcoholic Fatty Liver Disease Degree Measured Using Controlled...

Area of Science:

• Dermatology and Hepatology
• Metabolic Syndrome Research

Background:

• Psoriasis is increasingly linked to metabolic disorders.
• The relationship between psoriasis and nonalcoholic fatty liver disease (NAFLD) requires further investigation.

Purpose of the Study:

• To determine the correlation between psoriasis severity and the degree of NAFLD.
• To assess the relationship between psoriasis extent and liver steatosis.

Main Methods:

• Cross-sectional study of adult psoriasis patients.
• Psoriasis severity assessed using Psoriasis Area and Severity Index (PASI) and Body Surface Area (BSA).
• NAFLD degree measured by Controlled Attenuation Parameter (CAP); correlated with PASI and BSA.

Main Results:

• 77.8% of psoriasis patients had NAFLD.
• No significant correlation found between PASI and NAFLD (CAP score).
• Significant correlation observed between psoriasis Body Surface Area (BSA) and NAFLD (CAP score), as well as with BMI and abdominal circumference.

Conclusions:

• Psoriasis extension, indicated by BSA, correlates with NAFLD severity.
• Further research is needed to explore the impact of psoriasis therapies on the NAFLD link.