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A strip test for detecting Candida in the oral cavity
Oral Surgery, Oral Medicine, and Oral Pathology
|August 1, 1977
Summary
Microstix, a new Candida screening method, accurately detects oral candidiasis in severely ill patients. While slightly less sensitive in healthy carriers, it is recommended for clinical screening due to its reliability.
Area of Science:
- Oral medicine
- Microbiology
- Diagnostic methods
Background:
- Oral candidiasis is a common fungal infection.
- Accurate and rapid diagnostic methods are crucial for timely treatment.
- Conventional culture methods can be time-consuming.
Purpose of the Study:
- To evaluate the reliability of the Microstix method for detecting Candida in oral samples.
- To compare Microstix with conventional culture methods (Sabouraud's agar and yeast extract).
- To assess the utility of Microstix for screening oral Candida carriage.
Main Methods:
- Screening of 120 individuals for oral Candida presence.
- Culturing salivary samples using Sabouraud's agar, yeast extract, and the Microstix strip.
- Comparing diagnostic results between conventional methods and Microstix.
Main Results:
- Microstix demonstrated 100% reliability in detecting candidiasis in severely ill patients.
- In healthy controls, Microstix identified fewer Candida carriers (41/93) compared to conventional methods (45/93).
- Discrepancies may be due to Microstix's sensitivity limit (5.10^2 yeast/mL).
Conclusions:
- The Microstix strip is a reliable tool for diagnosing clinically suspected oral candidiasis.
- It is highly effective for screening oral Candida carriage, especially in clinical settings.
- Further evaluation of its sensitivity limit may be warranted for asymptomatic carriers.