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Published on: November 5, 2021
SARS-CoV-2 infection in an infant with severe dilated cardiomyopathy
Aslak Widerøe Kristoffersen1, Per Kristian Knudsen2, Thomas Møller1
1Department of Paediatric Cardiology, Division of Paediatric and Adolescent Medicine, Oslo University Hospital, Oslo, Norway.
Insights
A young child with severe heart disease experienced a mild SARS-CoV-2 infection. Close monitoring and specific treatments were crucial for managing her cardiac condition during the viral illness.
Area of Science:
- Pediatric Cardiology
- Infectious Diseases
- Neonatal Care
Background:
- Severe dilated cardiomyopathy in infants can result from neonatal enterovirus myocarditis.
- Management of pediatric heart conditions often involves diuretics and inotropes like milrinone.
- SARS-CoV-2 (COVID-19) infection presents unique challenges in immunocompromised or critically ill children.
Observation:
- A 4.5-month-old infant with pre-existing severe dilated cardiomyopathy contracted SARS-CoV-2.
- The child presented with high fever and gastrointestinal symptoms, indicative of a mild COVID-19 course.
- Cardiac function, assessed via echocardiography, remained stable throughout the SARS-CoV-2 infection.
Findings:
- Despite a mild presentation of SARS-CoV-2, the infant required intensive monitoring.
- Treatment focused on hemodynamic stability, including maintaining normal heart rate and fluid balance.
- The underlying severe cardiac condition necessitated a compound treatment approach.
Implications:
- Even mild SARS-CoV-2 infections necessitate careful management in children with severe underlying cardiac disease.
- This case highlights the importance of integrated care for pediatric patients with complex comorbidities during viral outbreaks.
- Close cardiac monitoring and tailored medical interventions are vital for preventing complications in vulnerable pediatric populations.
Abstract:
A four- and a half-month-old girl with severe dilated cardiomyopathy due to neonatal enterovirus myocarditis, treated with diuretics and milrinone for the past 4 months, was infected with SARS-CoV-2. The disease course was characterised by high fever and gastrointestinal symptoms. Cardiac function, as measured by echocardiography, remained stable. The treatment focused on maintaining a normal heart rate and a stable fluid balance. In children with severe underlying cardiac disease, even a mild SARS-CoV-2 infection can require close monitoring and compound treatment.
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