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Updated: Dec 3, 2025

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
[Sickle cell disease and pregnancy]
Thomas Christensen1, Amina Nardo-Marino, Andreas Glenthøj
1thomasc87@hotmail.com.
Sickle cell disease (SCD) is the most common severe hereditary disease worldwide. SCD during pregnancy is associated with increased incidence of perinatal mortality, premature labour, foetal growth restriction, and acute painful crises. Global migration has contributed to a greater geographical spread of individuals with hereditary haemoglobinopathies. This has led to an increased incidence of pregnant women with SCD in Denmark. In this review, we descibe the aetiology, assessment, antenatal care and treatment of pregnant women with SCD.
Sickle cell disease (SCD) is the most common severe hereditary disease worldwide. SCD during pregnancy is associated with increased incidence of perinatal mortality, premature labour, foetal growth restriction, and acute painful crises. Global migration has contributed to a greater geographical spread of individuals with hereditary haemoglobinopathies. This has led to an increased incidence of pregnant women with SCD in Denmark. In this review, we descibe the aetiology, assessment, antenatal care and treatment of pregnant women with SCD.
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