Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pneumonia II: Pathophysiology01:29

Pneumonia II: Pathophysiology

2.1K
The pathophysiology of pneumonia involves the following steps:
2.1K
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

568
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
568
Pneumonia V: Nursing management and Prevention01:30

Pneumonia V: Nursing management and Prevention

3.1K
Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
3.1K
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

662
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
662
Chronic Obstructive Pulmonary Disease01:22

Chronic Obstructive Pulmonary Disease

2.0K
COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
2.0K
Pneumonia IV: Management01:28

Pneumonia IV: Management

624
The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
624

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development and <i>in-vivo</i> efficacy of Leicester-UTI1 phage cocktail that targets ESBL-associated <i>Klebsiella</i> from urinary tract infections.

Microbiology spectrum·2026
Same author

Quantitative analysis of bacterial cell-cell communication at the single-cell level using microdroplet arrays.

Communications biology·2026
Same author

Label-free microscopy enables high-throughput identification of genes controlling biofilm development.

mBio·2026
Same author

Transcriptional regulation of the pneumococcal capsule can dictate serotype-specific infection.

Nature communications·2026
Same author

A small periplasmic protein governs broad physiological adaptations in Vibrio cholerae via regulation of the DbfRS two-component system.

Nature communications·2025
Same author

Label-free microscopy enables high-throughput identification of genes controlling biofilm development.

bioRxiv : the preprint server for biology·2025
Same journal

RNF31 restricts EV-A71 replication through innate immune activation and VP4 degradation, and is antagonized by viral 3C proteases.

PLoS pathogens·2026
Same journal

How Saprolegniales became successful parasites.

PLoS pathogens·2026
Same journal

Anti-malarial contact dependent blocking of transmission of Plasmodium vivax by Anopheles darlingi mosquito vector.

PLoS pathogens·2026
Same journal

A single Citrobacter rodentium infection in Pink1 knockout and wild-type mice leads to regional blood-brain-barrier perturbation and limited microglial activation without dopamine neuron axon terminal loss.

PLoS pathogens·2026
Same journal

Correction: Structural basis for substrate recognition and inhibition of thioredoxin glutathione reductase from Schistosoma japonicum: Implications for antiparasitic development.

PLoS pathogens·2026
Same journal

Balancing under constraint: Structural insights into norovirus evolution and antigenic innovation.

PLoS pathogens·2026
See all related articles

Related Experiment Video

Updated: Dec 3, 2025

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
11:32

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria

Published on: February 23, 2014

15.4K

The pneumococcal social network.

Surya D Aggarwal1, Hasan Yesilkaya2, Suzanne Dawid3,4

  • 1Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America.

Plos Pathogens
|October 29, 2020
PubMed
Summary
This summary is machine-generated.

Streptococcus pneumoniae uses secreted peptides for communication and survival. Understanding these signaling systems offers new strategies against pneumococcal infections.

More Related Videos

Experimental Human Pneumococcal Carriage
07:47

Experimental Human Pneumococcal Carriage

Published on: February 15, 2013

16.0K
Constructing Mutants in Serotype 1 Streptococcus pneumoniae strain 519/43
06:06

Constructing Mutants in Serotype 1 Streptococcus pneumoniae strain 519/43

Published on: September 11, 2020

2.0K

Related Experiment Videos

Last Updated: Dec 3, 2025

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
11:32

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria

Published on: February 23, 2014

15.4K
Experimental Human Pneumococcal Carriage
07:47

Experimental Human Pneumococcal Carriage

Published on: February 15, 2013

16.0K
Constructing Mutants in Serotype 1 Streptococcus pneumoniae strain 519/43
06:06

Constructing Mutants in Serotype 1 Streptococcus pneumoniae strain 519/43

Published on: September 11, 2020

2.0K

Area of Science:

  • Microbiology
  • Bacterial Pathogenesis
  • Molecular Biology

Background:

  • Gram-positive bacteria utilize secreted peptides for population control.
  • Streptococcus pneumoniae, a human pathogen, employs diverse secreted peptides.

Purpose of the Study:

  • To review the mechanistic and functional aspects of secreted peptides in Streptococcus pneumoniae.
  • To explore peptide features, transport, receptors, and their role in pathogenesis.

Main Methods:

  • Review of existing literature on pneumococcal secreted peptides.
  • Analysis of peptide sequence features, transport mechanisms, and receptor interactions.
  • Examination of factors influencing carriage and pathogenesis, including genetic diversity and microbial competition.

Main Results:

  • Identified three major categories of secreted peptides: double-glycine, RRNPP-binding, and lanthionine-containing peptides.
  • Revealed a complex network of interacting signaling systems with integrated pathways.
  • Highlighted opportunities for peptide crosstalk, quorum sensing, and inter-species interactions.

Conclusions:

  • Pneumococcal peptide signaling is intricate, involving multiple integrated pathways.
  • Understanding these peptide-mediated behaviors is crucial for developing novel anti-infective strategies.
  • Further research into peptide signaling can lead to targeted therapies against Streptococcus pneumoniae.