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Burkholderia cenocepacia keratitis
Geeta Behera1, Radha Sugumar2, Sujata Sistla2
1Department of Ophthalmology, Jawaharlal Institute of Post-Graduate Medical Education and Research (JIPMER), Puducherry, India.
Indian Journal of Ophthalmology
|October 30, 2020
Summary
This case report details the first documented ocular infection with Burkholderia cenocepacia, a bacterium identified via MALDI-TOF MS. The patient successfully healed after treatment with topical moxifloxacin.
Area of Science:
- Ophthalmology
- Microbiology
- Infectious Diseases
Background:
- Corneal transplantation (keratoplasty) can fail due to various complications.
- Bacterial keratitis is a serious infection that can threaten vision, especially in compromised corneas.
- Ocular infections by unusual bacteria can be challenging to diagnose and treat.
Observation:
- A 33-year-old female with a history of failed keratoplasty and glaucoma developed bacterial keratitis after corneal trauma.
- Corneal cultures identified Burkholderia cenocepacia using matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS).
Findings:
- The patient's bacterial keratitis, caused by Burkholderia cenocepacia, resolved within one month with topical moxifloxacin treatment.
- This represents the first reported case of ocular Burkholderia cenocepacia infection.
Implications:
- Burkholderia cenocepacia may be an underreported cause of bacterial keratitis, particularly in patients with prior ocular surgery or trauma.
- Prompt identification and appropriate antibiotic therapy are crucial for managing rare bacterial corneal infections.
- This case highlights the importance of considering a broad spectrum of aerobic organisms in the differential diagnosis of microbial keratitis.
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