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Tracheobronchial amyloidosis in primary Sjögren syndrome: A case report
1Department of Rheumatology and immunology, the second people's Hospital of Ningxia.
Rationale:
Tracheobronchial amyloidosis (TBA) associated with Sjögren syndrome is very rare. Here, we describe a case with this phenomenon, in order to better understand the condition.
Patient Concerns:
A 52-year-old woman presented after 6 months of coughing, sputum, and dyspnea. Chest computed tomography revealed thickened bronchial walls, which were irregular on the left side the trachea. She had a history of dry eye and dry mouth of at least 3 years' duration.
Diagnoses:
Sjögren syndrome was diagnosed based on her symptoms, ophthalmological and parotid examination, and immunological and autoantibody tests. The diagnosis of TBA was confirmed by Congo red staining of a tracheal biopsy.
Interventions:
The patient was given glucocorticoids without any other immunosuppressants.
Outcomes:
The symptoms improved after 6 months.
Lessons:
TBA associated with Sjögren syndrome is a rare condition. TBA is characterized by amyloid deposition to the trachea in the absence of systemic amyloidosis. Diagnosis requires tissue biopsy with demonstration of amyloid deposition.
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