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Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

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Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

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As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
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Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

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Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

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Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are...
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FDA Approved Drugs: Changes to Approved Drugs01:26

FDA Approved Drugs: Changes to Approved Drugs

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Post-approval, manufacturers may modify an approved new or generic drug product. Such modifications can encompass alterations in the Active Pharmaceutical Ingredient (API), manufacturing process, formulation, batch size, manufacturing site, and container closure system (FDA Guidance for Industry, April 2004). Often, a drug product may undergo multiple changes.These modifications require careful evaluation to determine their potential impact on the drug product's identity, strength, quality,...
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Restorative Care01:19

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Restorative care is provided once a patient has been discharged from a healthcare facility and requires additional services. The additional services include home care, rehabilitation programs, and extended care. Restorative care centers help the patient regain their previous level of functioning or acquire a new level of functioning due to the incapacitating effects of a disease or a disability. It aims to assist patients in enhancing their quality of life by encouraging independence,...
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The Long Term Care Pharmacy World is Changing.

Paul Baldwin

    The Senior Care Pharmacist
    |October 30, 2020
    PubMed
    Summary

    The COVID-19 pandemic is reshaping the long-term care industry. Pharmacists must adapt to these lasting changes to ensure quality patient care.

    Area of Science:

    • Gerontology
    • Public Health
    • Pharmaceutical Sciences

    Background:

    • The COVID-19 pandemic has significantly impacted healthcare systems globally.
    • Long-term care facilities are particularly vulnerable to infectious disease outbreaks.
    • The pandemic necessitates a re-evaluation of operational models within the long-term care sector.

    Purpose of the Study:

    • To analyze the potential long-term transformations in the long-term care industry due to COVID-19.
    • To highlight the evolving role and responsibilities of pharmacists in this changing landscape.
    • To provide guidance for pharmacists on adapting to post-pandemic challenges in long-term care.

    Main Methods:

    • Review of current literature on pandemic impacts on healthcare.
    • Analysis of trends in long-term care operations and pharmaceutical services.

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  • Synthesis of expert opinions and recommendations for industry adaptation.
  • Main Results:

    • Anticipated shifts in infection control protocols and facility design.
    • Increased demand for telehealth and remote patient monitoring services.
    • Evolving pharmaceutical care models focusing on medication management and public health.

    Conclusions:

    • The long-term care industry will undergo fundamental changes post-COVID-19.
    • Pharmacists play a crucial role in navigating these changes through proactive adaptation.
    • Continuous professional development and strategic adjustments are essential for pharmacists in long-term care.