Related Experiment Video
Updated: Dec 3, 2025

Modeling the Functional Network for Spatial Navigation in the Human Brain
Published on: October 13, 2023
Impact of road network structure on dementia-related missing incidents: a spatial buffer approach
Vaisakh Puthusseryppady1, Ed Manley2,3, Ellen Lowry1,4
1Norwich Medical School, 2.04 Bob Champion Research and Education Building, University of East Anglia, Norwich, NR4 7TJ, UK.
Abstract:
Dementia-related missing incidents are a highly prevalent issue worldwide. Despite being associated with potentially life-threatening consequences, very little is still known about what environmental risk factors may potentially contribute to these missing incidents. The aim of this study was to conduct a retrospective, observational analysis using a large sample of police case records of missing individuals with dementia (n = 210). Due to the influence that road network structure has on our real world navigation, we aimed to explore the relationship between road intersection density, intersection complexity, and orientation entropy to the dementia-related missing incidents. For each missing incident location, the above three variables were computed at a 1 km radius buffer zone around these locations; these values were then compared to that of a set of random locations. The results showed that higher road intersection density, intersection complexity, and orientation entropy were all significantly associated with dementia-related missing incidents. Our results suggest that these properties of road network structure emerge as significant environmental risk factors for dementia-related missing incidents, informing future prospective studies as well as safeguarding guidelines.
More Related Videos
08:43Application of Granger Causality Analysis of the Directed Functional Connection in Alzheimer's Disease and Mild Cognitive Impairment
Published on: August 7, 2017
06:17Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function
Published on: January 26, 2024
Related Concept Videos
Design Example: Alignment of a Road Line Using GIS
Manipulation and Analysis