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Postcontrast Fluid-Attenuated Inversion Recovery (FLAIR) Sequence MR Imaging in Detecting Intracranial Pathology

Ajit Mahale1, Shaloo Choudhary1, Sonali Ullal1

  • 1Department of Radiodiagnosis, Kasturba Medical College Mangalore, MAHE Dakshina Kannada, Karnataka 575001, India.

Radiology Research and Practice
|October 30, 2020
PubMed
Abstract

Insights

Delayed postcontrast T2 FLAIR MRI is superior for detecting meningeal enhancement in meningitis. This sequence, along with T1 FLAIR, aids in evaluating intracranial pathologies and brain lesions.

Area of Science:

  • Neuroradiology
  • Medical Imaging
  • Neuroscience

Background:

  • Accurate detection of meningeal and parenchymal lesions is crucial for diagnosing intracranial pathology.
  • Fluid-attenuated inversion recovery (FLAIR) MRI sequences are utilized for evaluating postcontrast enhancement.

Purpose of the Study:

  • To assess the efficacy of FLAIR MRI sequences in delineating postcontrast enhancement in the brain.
  • To compare the diagnostic performance of different FLAIR sequences for intracranial lesions.

Main Methods:

  • A prospective, hospital-based observational study involving 66 patients with intracranial pathology.
  • Assessment of postcontrast T1 MTC, delayed postcontrast T2 FLAIR, and T1 FLAIR images by experienced radiologists.

Main Results:

  • Delayed postcontrast T2 FLAIR identified 28 cases of meningeal enhancement.
  • Low-grade gliomas showed enhancement on postcontrast T1 MTC; multiple sclerosis lesions were better visualized on postcontrast T1 FLAIR.
  • Meningioma exhibited brighter enhancement on delayed postcontrast T2 FLAIR.

Conclusions:

  • Delayed postcontrast T2 FLAIR surpasses T1 MTC for detecting meningeal enhancement in meningitis and carcinomatosis.
  • Intra-axial lesions were more conspicuous or similar on delayed postcontrast T2 FLAIR compared to T1 MTC.
  • Delayed postcontrast T1 FLAIR offered superior anatomic delineation of intra-axial lesions.

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