Related Experiment Video
Updated: Dec 3, 2025

Non-invasive Assessment of Dorsiflexor Muscle Function in Mice
Published on: January 17, 2019
Musculus peroneus longus in foetal period.
A Karykowska1, Z A Domagała2, B Gworys3
1Department of Anthropology, Wroclaw University of Environmental and Life Sciences, Wroclaw, Poland.
The fetal development of the lateral leg compartment muscle, musculus peroneus longus (MPL), shows significant growth in size and variable attachment points. This study details MPL anatomical changes during prenatal development.
Area of Science:
- Anatomy
- Embryology
- Human Morphology
Background:
- The lateral compartment of the leg is a common trauma site, necessitating detailed anatomical knowledge.
- The musculus peroneus longus (MPL) is superficially located within this compartment.
- Existing research lacks detailed fetal anatomical analysis of the MPL.
Purpose of the Study:
- To investigate the variability of metric and morphological parameters of the musculus peroneus longus (MPL) during prenatal development.
- To provide detailed anatomical data on MPL during fetal development.
Main Methods:
- Analysis of 207 human fetuses (113-222 days gestation).
- Utilized standard dissection techniques on preserved specimens.
- Evaluated metric parameters and muscle attachment topography.
Main Results:
- MPLs increased by approximately 60% in length/width and 100% in thickness during the studied prenatal period.
- Variability in the origin and insertion topography of the MPL was observed.
- Statistically significant sex-based differences were noted in muscle attachment topography.
Conclusions:
- The origin and insertion sites of the musculus peroneus longus (MPL) exhibit considerable variability during fetal development.
- Understanding this variability is crucial for clinical applications in leg trauma and surgery.
Related Concept Videos
Muscles of the Leg that Move the Foot and Toes
Anterior Compartment
The anterior compartment includes muscles that contribute to the dorsiflexion of the foot. This compartment houses the tibialis anterior, extensor hallucis longus, and extensor digitorum longus muscles....
Muscles that Move the Leg
Anterior Compartment
The quadriceps femoris, the most visible muscle of the anterior compartment, is integral for leg extension and thigh flexion. It is formed by merging four distinct muscles — the vastus lateralis, vastus medialis, vastus intermedius, and rectus femoris. The quadriceps tendon, a shared tendon of the four quadriceps muscles, is affixed...
Bones of the Lower Limb: Femur and Patella
Bones of the Lower Limb: Tibia and Fibula
Changes in the Appendicular Skeleton with Age
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Muscles of the Pelvic Floor and Perineum
Perineal Layer
The perineum is a diamond-shaped area below the pelvic diaphragm, divided into an anterior urogenital triangle that contains the external genitals and a posterior anal triangle housing the anus. The urogenital...

