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Updated: Dec 3, 2025

Platelet-Derived Extracellular Vesicle Functionalization of Ti Implants
Published on: August 5, 2021
Surface modification for osseointegration of Ti6Al4V ELI using powder mixed sinking EDM
Mohammad Pervez Mughal1, Muhammad Umar Farooq2, Jabir Mumtaz3
1Department of Industrial and Manufacturing Engineering, University of Engineering and Technology, Lahore, Pakistan.
Abstract:
Biomedical implant rejection due to micromotion and inflammation around an implant leads to osteolysis and eventually has an implant failure because of poor osseointegration. To enhance osseointegration, the implant surface modification both at the nano and micro-scale levels is preferred to result in an enhanced interface between the body tissue and implant. The present study focuses on the modification of the surface of Titanium (α+β) ELI medical grade alloy using powder-mixed electric discharge machining (PMEDM). Pulse current, on/off time, and various silicon carbide (SiC) powder concentrations are used as input parameters to comprehend desired surface modifications. Powder concentration is considered as the most important factor to control surface roughness and recast layer depth. A significant decrease in surface fracture density and roughness is observed using a 20 g/l concentration of SiC particles. Elemental mapping analysis has confirmed the migration of Si and the generation of promising surface texture and chemistry. Oxides and carbides enriched surface improved the microhardness of the re-solidified layer from 320 HV to 727 HV. Surface topology reveals nano-porosity (50-200 nm) which enhances osseointegration due to the absorption of proteins especially collagen to the surface.
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