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Therapeutic strategies targeting somatic stem cells: Chemical approaches
1Institute of Cancer Research, Shenzhen Bay Laboratory, Shenzhen 518132, China.
Abstract:
Therapeutic modulation of fate and behavior of somatic stem cells can generate safe and functional cells ex vivo for cell-based therapy, or to repair and regenerate damaged tissues in vivo. Chemical approaches involving small molecules have provided promising approaches for modulating cellular fate and function. These strategies offer opportunities that support regenerative medicine. Here, we discuss strategies targeting somatic stem cells through chemical approaches, highlighting their progression as well as future prospects.
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