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Related Concept Videos

Opioid Analgesics: Synthetic and Semisynthetic Opioids01:15

Opioid Analgesics: Synthetic and Semisynthetic Opioids

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Synthetic and semisynthetic opioids are pivotal in pain management and tackling opioid addiction. Semisynthetic opioids, including morphinans (morphine derivatives), oxycodone, oxymorphone, hydrocodone, and hydromorphone, have improved pharmacokinetic profiles compared to morphine. Additionally, heroin and 6-MAM (6-Monoacetylmorphine) show better CNS penetration than morphine due to heightened lipid solubility. Hydromorphone, a potent opioid, undergoes hepatic metabolism to form the active...
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Opioid Analgesics: Morphine and Other Natural Cogeners01:20

Opioid Analgesics: Morphine and Other Natural Cogeners

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Opioids are a class of drugs that mimic endogenous opioid peptides and act on opioid receptors, and help in pain relief. These compounds are classified as natural, synthetic, or semi-synthetic. Natural opioids, like morphine, codeine, and thebaine, are derived from the opium poppy plant (Papaver somniferum or Papaver album) and are termed opiates. Synthetic opioids are artificial, while semi-synthetic opioids combine natural and synthetic compounds. Morphine, a prototypical opioid, possesses a...
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Analgesia and Pain Management01:25

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Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
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Opioid Receptors: Overview01:22

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Opioid receptors, including the mu (μ, MOR), delta (δ, DOR), and kappa (κ, KOR) types, belong to the rhodopsin family of G protein-coupled receptors. These receptors are located throughout the central and peripheral nervous systems and in non-neuronal tissues such as macrophages and astrocytes. Opioid receptor ligands can be categorized into agonists or antagonists. Highly selective agonists include [d-Ala2, MePhe4, Gly(ol)5]-enkephalin or DAMGO for MOR, [D-Pen2,...
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Prescription, Nonprescription and Orphan Drugs01:02

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Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
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Drugs Affecting GI Tract Motility: Opioids as Antidiarrheal Agents01:17

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Diarrhea, a condition marked by frequent loose or watery bowel movements, can be triggered by multiple factors such as viral or bacterial infections, food intolerances, anxiety, medications, and digestive disorders. Symptoms may include abdominal pain, bloating, nausea, and cramping. Severe or prolonged diarrhea can lead to complications like electrolyte imbalances, malnutrition, and dehydration if left untreated.
Opioids, widely used antidiarrheal agents, mitigate diarrhea by slowing down...
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    Area of Science:

    • Public Health
    • Health Informatics
    • Medical Practice Management

    Background:

    • The COVID-19 pandemic created unprecedented challenges for healthcare systems globally.
    • Physicians faced significant disruptions in patient care delivery and practice operations.
    • The need for adaptive healthcare solutions became critical.

    Purpose of the Study:

    • To examine the role of telemedicine in mitigating the negative effects of the COVID-19 pandemic on Texas physicians.
    • To understand how telehealth services assisted medical practitioners in managing practice fallout.

    Main Methods:

    • Analysis of physician experiences with telemedicine during the COVID-19 pandemic in Texas.
    • Qualitative or quantitative assessment of telemedicine adoption and its impact.

    Main Results:

    • Telemedicine adoption surged among Texas physicians in response to the pandemic.
    • Telehealth facilitated continued patient access to care and supported practice continuity.
    • Physicians reported that telemedicine helped alleviate some of the operational and clinical burdens.

    Conclusions:

    • Telemedicine proved to be an essential tool for Texas physicians navigating the COVID-19 crisis.
    • Sustained integration of telemedicine can enhance healthcare resilience and adaptability.
    • Policy and infrastructure support for telemedicine are vital for future public health preparedness.