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MRI-guided breast biopsy based on diffusion-weighted imaging: a feasibility study.

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Diffusion-weighted imaging (DWI) is a reliable technique for MRI-guided breast biopsies, enabling accurate lesion targeting and device localization without contrast agents. This method proves feasible for both mass and non-mass lesions.

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Area of Science:

  • Radiology and Imaging
  • Oncology
  • Surgical Procedures

Background:

  • MRI-guided breast biopsy typically requires contrast agents for lesion targeting.
  • Expert staff and prior MR imaging are essential for these procedures.
  • Alternative imaging techniques are sought to improve efficiency and reduce contrast use.

Purpose of the Study:

  • To evaluate the feasibility of Diffusion-Weighted Imaging (DWI) for lesion targeting in MRI-guided breast biopsies.
  • To assess the accuracy of device positioning using DWI during biopsy procedures.
  • To determine if DWI can replace or supplement standard imaging protocols.

Main Methods:

  • Retrospective review of 87 MRI-guided breast biopsy procedures.
  • Inclusion of 64 procedures where lesions were detectable on a preliminary DWI sequence (b=1300 s/mm²).
  • DWI sequences were integrated to localize lesions, biopsy devices, and assess site marker placement.

Main Results:

  • Lesions ranged from 5 mm (mass) to 90 mm (non-mass).
  • The biopsy needle was visualized on DWI in 96.9% of cases.
  • The site marker was recognizable on DWI in 95.5% of cases where final DWI was acquired.

Conclusions:

  • DWI is a cost-effective and highly reliable technique for targeting both mass and non-mass breast lesions detectable by DWI (minimum 5 mm).
  • DWI facilitates accurate localization of the biopsy device and confirmation of site marker deployment.
  • DWI offers a feasible alternative to contrast agent administration for lesion targeting in MRI-guided biopsies.