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[Cutaneous manifestations of ulcerative colitis]
1Serviço de Medicina 2 (Gastrenterologia), Hospital de Santa Maria, Lisboa.
Medicina Cutanea Ibero-Latino-Americana
|January 1, 1987
Summary
A significant portion of ulcerative colitis patients experience skin and mucosal lesions, including oral and perianal complications. These mucocutaneous manifestations often correlate with joint, eye, and liver involvement.
Area of Science:
- Gastroenterology
- Dermatology
- Ophthalmology
- Rheumatology
Context:
- Ulcerative colitis (UC) is a chronic inflammatory bowel disease.
- Extraintestinal manifestations (EIMs) are common in UC patients.
- Mucocutaneous involvement represents a significant category of EIMs.
Purpose:
- To investigate the prevalence and types of skin and mucosal lesions in patients with ulcerative colitis.
- To identify associated systemic complications, including articular, ocular, and hepatic changes.
Summary:
- Out of 210 ulcerative colitis cases, 41 (19.5%) presented with skin and mucosal lesions.
- Cutaneous lesions included maculopapular rashes, erythema nodosum, and pyoderma gangrenosum.
- Oral lesions (aphthae) and perianal lesions (fissures, fistulas) were also common.
- Multiple mucocutaneous complications occurred in 17.1% of patients.
- Associated systemic findings included articular (36.6%), ocular (9.8%), and hepatic (2.4%) manifestations.
- Colitic arthritis and keratoconjunctivitis sicca were the most frequent joint and eye conditions.
Impact:
- Highlights the high frequency of mucocutaneous involvement in ulcerative colitis.
- Underscores the need for comprehensive evaluation of extraintestinal manifestations in UC patients.
- Informs clinical practice regarding the recognition and management of associated systemic conditions.