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Related Experiment Video

Updated: Dec 3, 2025

Use of the Scissor-Type Knife During the Peroral Endoscopy Myotomy Procedure for the Treatment of Achalasia
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Per Oral Zenker Diverticulotomy.

Harry J Wong1, Michael B Ujiki2

  • 1Department of Surgery, University of Chicago Medicine, Chicago, IL, USA; Department of Surgery, NorthShore University HealthSystem, 2650 Ridge Avenue, Evanston, IL 60201, USA.

The Surgical Clinics of North America
|October 31, 2020
PubMed
Summary

Zenker diverticulum (ZD) management involves surgical division of the cricopharyngeus muscle. A novel flexible endoscopic approach, per oral endoscopic myotomy, offers a safe and effective treatment option for ZD with low morbidity.

Keywords:
DiverticulotomyFlexible endoscopySTESDSubmucosal tunnelingZ-POEMZenker diverticulum

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Area of Science:

  • Gastroenterology
  • Surgical Innovation
  • Esophageal Disorders

Background:

  • Zenker diverticulum (ZD) is a rare surgical condition primarily affecting the elderly.
  • Current management aims for cricopharyngeus muscle division.
  • Treatment options include open surgery and various endoscopic diverticulotomy techniques.

Purpose of the Study:

  • To review current evidence and management strategies for Zenker diverticulum.
  • To describe a novel flexible endoscopic submucosal tunneling technique for cricopharyngeal myotomy.
  • To evaluate the safety and efficacy of this new approach.

Main Methods:

  • Review of current literature on Zenker diverticulum management.
  • Detailed description of a novel flexible endoscopic submucosal tunneling technique for per oral endoscopic myotomy (POEM).
  • Assessment of patient selection and tailored operative interventions.

Main Results:

  • Per oral endoscopic myotomy (POEM) using submucosal tunneling is demonstrated as a safe and effective treatment for ZD.
  • This flexible endoscopic approach offers a viable alternative with low morbidity.
  • Careful patient selection is crucial for successful surgical intervention.

Conclusions:

  • Zenker diverticulum is a treatable condition requiring precise surgical intervention.
  • Per oral endoscopic myotomy represents a significant advancement in the endoscopic management of ZD.
  • Tailoring treatment to individual patient characteristics ensures optimal outcomes.