Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

New method for cardiac transplantation.

Y Umeki1, H P Weinrib, C A MacLeod

  • 1Department of General Surgery, Rush-Presbyterian-St. Luke's Medical Center, Chicago, IL 60612.

Microsurgery
|January 1, 1987
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Posttransplant reduction in preexisting donor-specific antibody levels after belatacept- versus cyclosporine-based immunosuppression: Post hoc analyses of BENEFIT and BENEFIT-EXT.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2018
Same author

De novo donor-specific antibodies in belatacept-treated vs cyclosporine-treated kidney-transplant recipients: Post hoc analyses of the randomized phase III BENEFIT and BENEFIT-EXT studies.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2018
Same author

The Road to HLA Antibody Evaluation: Do Not Rely on MFI.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2017
Same author

HLA compatibility assessment and management of highly sensitized patients under the new kidney allocation system (KAS): A 2016 status report from twelve HLA laboratories across the U.S.

Human immunology·2016
Same author

High-Resolution HLA Typing for Sensitized Patients: Advances in Medicine and Science Require Us to Challenge Existing Paradigms.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2015
Same author

Apolipoprotein L1 gene variants in deceased organ donors are associated with renal allograft failure.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2015
Same journal

Symani-Assisted Microsurgery in Head and Neck Reconstruction: A Systematic Review of Indications, Techniques, and Pooled Analysis of Clinical Outcomes.

Microsurgery·2026
Same journal

Proposing Objective 3D Facial Surface Scanning to Evaluate Surgical Outcomes in Facial Lymphedema.

Microsurgery·2026
Same journal

Closure of Tracheoesophageal Fistula Employing the Superficial Circumflex Iliac Artery Perforator (SCIP) Flap: Report of Three Cases.

Microsurgery·2026
Same journal

Umbilical Inset Incision Type Influences Abdominal Donor Site Healing in Autologous Breast Reconstruction.

Microsurgery·2026
Same journal

Evaluating the Efficacy and Utility of Preoperative Computed Tomography Angiography in Perforator Flap Surgeries: A Systematic Review and Meta-Analysis.

Microsurgery·2026
Same journal

Recipient Vessel Selection in Free Flap Phalloplasty: A Systematic Review and Single-Arm Meta-Analysis.

Microsurgery·2026
See all related articles

This study presents a novel surgical technique for rat cardiac transplantation, addressing donor-recipient vessel size discrepancies. The method facilitates future research into graft rejection mechanisms.

Area of Science:

  • Cardiovascular Surgery
  • Transplantation Immunology
  • Surgical Innovation

Background:

  • Rat cardiac transplantation is a valuable research model.
  • Femoral transplantation offers advantages over peritoneal transplantation.
  • A significant challenge is the disparity in donor and recipient vessel sizes.

Purpose of the Study:

  • To describe a new surgical technique for rat cardiac transplantation in the femoral region.
  • To overcome the donor-recipient vessel size mismatch.
  • To facilitate the study of graft rejection.

Main Methods:

  • End-in-end anastomosis of donor aorta to recipient femoral artery.
  • End-to-end anastomosis of donor pulmonary artery to recipient femoral vein.
  • Plication of excess donor vessel wall to manage size discrepancy.

Related Experiment Videos

Main Results:

  • The described technique successfully addresses the vessel size mismatch.
  • Results are comparable to previously established cardiac transplantation methods.
  • The method is suitable for studying immunological events in graft rejection.

Conclusions:

  • This innovative technique provides a viable solution for rat cardiac transplantation with mismatched vessels.
  • The plication method is effective in managing aortic and pulmonary artery anastomoses.
  • This approach holds significant promise for advancing research in transplantation immunology and graft rejection.