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Updated: Dec 2, 2025

A Rat Lung Transplantation Model of Warm Ischemia/Reperfusion Injury: Optimizations to Improve Outcomes
Published on: October 28, 2021
[Advances in the Pathogenesis,Prevention,and Treatment of Transfusion-related Acute Lung Injury]
Ai Hu1, Weiyun Chen1, Yuguang Huang1
1Department of Anesthesiology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
Abstract:
Transfusion-related acute lung injury(TRALI)is a severe pulmonary complication of transfusion and has been one of the leading causes of transfusion-associated deaths.However,the pathogenesis of TRALI is still unclear,and treatment and prevention of this condition also face huge challenges.Many recent studies have explored the roles of various effector cells and effector molecules in TRALI and possible related mechanisms based on various hypotheses,in order to find the key factors that induce TRALI and the potential prevention measures.This article reviews the pathogenesis,prevention,and treatment of TRALI.
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