Unplanned absorption of sunscreen ingredients: Impact of formulation and evaluation methods

Rodrigo Collina Romanhole1, Ana Laura Masquetti Fava1, Louise Lacalendola Tundisi2

  • 1School of Medical Sciences, University of Campinas (Unicamp), Campinas, Brazil.

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Methods for Studying Drug Absorption: In situ01:09

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In situ experiments, such as the Doluisio method and Single-Pass Perfusion technique, provide critical insights into drug uptake by simulating in vivo conditions for drug absorption.
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Bioavailability Enhancement: Drug Permeability Enhancement01:27

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Body:After oral administration, poor permeability often limits the rate at which drugs are absorbed through the intestinal epithelium. Enhancing drug permeability is crucial for effective therapy, and several strategies have been developed to overcome this challenge.One effective strategy involves the use of lipid-based formulations. These formulations enhance dissolution and solubility, targeting physiological mechanisms to increase drug absorption. This includes stimulating bile salt...
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