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Updated: Dec 2, 2025

Measurement of Tissue Non-Heme Iron Content using a Bathophenanthroline-Based Colorimetric Assay
Published on: January 31, 2022
A Japanese female with chronic mild anemia and primary iron overloading disease
Yukinori Hattori1, Hiroyuki Kato2, Ayako Kato3
1Department of Pathology, Japan Community Health care Organization, Chukyo Hospital, Nagoya, Japan.
Abstract:
A 65-year-old woman died of congestive heart failure and diabetes mellitus. She had a history of mild anemia since adolescence, but received neither iron supplementation nor transfusion. The cirrhotic liver obtained at autopsy contained a large amount of iron. The heart and pancreas also had excess iron. Her iron overload may be due to excess iron absorption in the gut because of the absence of an iatrogenic background such as transfusion or iron supplementation.
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