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Updated: Dec 2, 2025
Application of End-to-end Anastomosis in Robotic Central Pancreatectomy
Published on: June 2, 2018
Minimally invasive vs open pancreatectomy for nonfunctioning pancreatic neuroendocrine tumors
Juwan Kim1, Ho Kyoung Hwang2, Woo Jung Lee2
1Department of Surgery, Yonsei University College of Medicine, Severance Hospital, Seoul 03722, South Korea.
Background:
The mainstay of treating nonfunctioning-pancreatic neuroendocrine tumors(NF-PNETs) is surgical resection. However, minimally invasive approaches to pancreatic resection for treating NF-PNETs are not widely accepted, and the long-term oncological outcomes of such approaches remain unknown.
Aim:
To determine the short- and long-term outcomes of minimally invasive pancreatic resection conducted in patients with NF-PNETs.
Methods:
Prospective databases from Severance Hospital were searched for 110 patients who underwent curative resection for NF-PNETs between January 2003 and August 2018.
Results:
The proportion of minimally invasive surgery (MIS) procedures performed for NF-PNET increased to more than 75% after 2013. There was no significant difference in post-operative complications (P = 0.654), including pancreatic fistula (P = 0.890) and delayed gastric emptying (P = 0.652), between MIS and open approaches. No statistically significant difference was found in disease-free survival between the open approach group and the MIS group (median follow-up period, 28.1 mo; P = 0.428). In addition, the surgical approach (MIS vs open) was not found to be an independent prognostic factor in treating NF-PNET patients [Exp(β) = 1.062; P = 0.929].
Conclusion:
Regardless of the type of surgery, a minimally invasive approach can be safe and feasible for select NF-PNET patients.
