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Published on: May 21, 2010
The Impact of Compulsivity and Impulsivity in Cerebellar Ataxia: A Case Series
Nadia Amokrane1,2, Chi-Ying R Lin1,2, Natasha A Desai1,2
1Department of Neurology, Columbia University Medical Center, New York, NY, US.
Background:
The cerebellum has recently been identified to have a key role in reward processing, and individuals with ataxia have been found to be more impulsive and compulsive as part of cerebellum-related cognitive and behavioral disturbances.
Case Report:
We reported five individuals with cerebellar ataxia who demonstrate impulsive and compulsive behaviors, including hobbyism, gambling, and compulsive medication use, to illustrate that these symptoms can be highly disabling.
Discussion:
These five cases provide examples of behavioral symptoms in cerebellar ataxia. Further investigations of the pathomechanism of these symptoms will advance our understanding of the cerebellum in cognition and behavior.
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