Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Acute Respiratory Failure-II01:21

Acute Respiratory Failure-II

820
Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
820
Respiratory Assessment: Purpose and Indications01:19

Respiratory Assessment: Purpose and Indications

1.5K
Respiratory assessment is a cornerstone of nursing assessments, crucial for the early detection of patient deterioration. This evaluation transcends routine procedures, representing a critical skill nurses must master to ensure optimal patient care.
Objectives and Importance:
The primary goal of respiratory assessment is to evaluate patients at early risk of clinical deterioration. Since respiratory distress often precedes other signs of declining health, breathing patterns and sounds become a...
1.5K
Acute Respiratory Failure-IV01:23

Acute Respiratory Failure-IV

391
Respiratory failure can manifest suddenly or gradually, characterized by a rapid decline in PaO2 and a rapid rise in PaCO2. This situation indicates a severe respiratory problem that may quickly become a life-threatening emergency. One of the early signs of hypoxemic Acute Respiratory Failure (ARF) is a change in mental status due to the brain's sensitivity to oxygen levels and changes in acid-base balance. Symptoms such as restlessness, confusion, and agitation suggest inadequate oxygen...
391
Physiological Control of Respiration01:23

Physiological Control of Respiration

5.3K
Introduction
Breathing, a seemingly passive process, is regulated by the respiratory center in the brainstem. This center coordinates the involuntary control of respirations, which means it occurs without conscious effort, ensuring a smooth and uninterrupted pattern.
Regulation of Ventilation
The body maintains ventilation by monitoring levels of carbon dioxide (CO2), oxygen (O2), and hydrogen ion concentration (pH) in the arterial blood. Among these factors, the level of CO2 plays a crucial...
5.3K
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.01:25

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

3.3K
Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
3.3K
Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

3.9K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
3.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Infectious Complications After Oral Corticosteroid Use in Otolaryngology.

The Laryngoscope·2025
Same author

Complications of Oral Corticosteroid Use in Otolaryngology.

The Annals of otology, rhinology, and laryngology·2024
Same author

Association Between Superior Canal Dehiscence Syndrome and Anxiety and Depressive Disorders.

The Laryngoscope·2024
Same author

Diagnostic Yield of Patients Undergoing Evaluation of Possible Superior Canal Dehiscence.

The Laryngoscope·2024
Same author

Increasing Prevalence of Voice Disorders in the USA: Updates in the COVID Era.

The Laryngoscope·2024
Same author

Risk of inpatient epistaxis admission related to oral anticoagulation medication use.

Laryngoscope investigative otolaryngology·2023

Related Experiment Video

Updated: Dec 2, 2025

Author Spotlight: Utilizing Traditional Chinese Acupuncture of the Ear to Improve Sleep Disorders
05:34

Author Spotlight: Utilizing Traditional Chinese Acupuncture of the Ear to Improve Sleep Disorders

Published on: August 18, 2023

3.0K

Does chronic rhinosinusitis relate to systemic hypoxemia?

Neil Bhattacharyya1

  • 1Department of Otolaryngology-Head and Neck Surgery Massachusetts Eye and Ear, Harvard Medical School Boston Massachusetts USA.

Laryngoscope Investigative Otolaryngology
|November 2, 2020
PubMed
Summary
This summary is machine-generated.

Chronic rhinosinusitis (CRS) does not cause systemic hypoxemia. However, some patients with CRS and nasal polyps (CRScNP) may exhibit low oxygen saturation, suggesting SpO2 assessment for this subgroup.

Keywords:
asthmachronic rhinosinusitisdyspneahypoxemiahypoxiaunified airway

More Related Videos

Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach
04:53

Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach

Published on: October 18, 2024

1.2K
Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure
08:17

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure

Published on: August 25, 2017

11.3K

Related Experiment Videos

Last Updated: Dec 2, 2025

Author Spotlight: Utilizing Traditional Chinese Acupuncture of the Ear to Improve Sleep Disorders
05:34

Author Spotlight: Utilizing Traditional Chinese Acupuncture of the Ear to Improve Sleep Disorders

Published on: August 18, 2023

3.0K
Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach
04:53

Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach

Published on: October 18, 2024

1.2K
Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure
08:17

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure

Published on: August 25, 2017

11.3K

Area of Science:

  • Otolaryngology
  • Pulmonology
  • Medical Diagnostics

Background:

  • Chronic rhinosinusitis (CRS) is a common inflammatory condition affecting the nasal passages and sinuses.
  • Systemic hypoxemia, a condition of abnormally low oxygen levels in the blood, can have various underlying causes.
  • The potential link between CRS and hypoxemia requires investigation to clarify diagnostic and treatment pathways.

Purpose of the Study:

  • To determine if chronic rhinosinusitis (CRS) is independently associated with systemic hypoxemia.
  • To compare oxygen saturation levels between patients with CRS (with and without nasal polyps) and a control group.
  • To identify any specific subgroups within CRS that might be at higher risk for hypoxemia.

Main Methods:

  • Retrospective analysis of outpatient otolaryngology visits over 12 months.
  • Inclusion criteria: diagnosis of CRS, no pulmonary disease, and recent oxygen saturation (SpO2) measurement.
  • Comparison of SpO2 measures (average, minimum, abnormal proportion) between CRS patients (CRSsNP, CRScNP) and otology controls using univariate and multivariate analyses.

Main Results:

  • No statistically significant difference in mean or minimum SpO2 was found between CRS patients (with or without nasal polyps) and controls after adjusting for age and sex.
  • A statistically significant difference was observed in the proportion of patients with abnormally low SpO2 (≤94%).
  • Specifically, 10.9% of CRScNP patients, 4.4% of CRSsNP patients, and 7.3% of controls had low SpO2 (P = .013).

Conclusions:

  • Chronic rhinosinusitis alone does not appear to cause systemic hypoxemia.
  • A notable subset of patients with chronic rhinosinusitis and nasal polyps (CRScNP) may present with abnormally low oxygen saturation.
  • Oxygen saturation assessment may be warranted for patients diagnosed with CRScNP.