Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Positron Emission Tomography01:29

Positron Emission Tomography

6.6K
Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
6.6K
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

349
Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
349
Computed Tomography01:10

Computed Tomography

7.7K
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
7.7K
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

282
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
282

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Unique presentation of immune thrombocytopenic purpura in adult osteopetrosis: A case report.

Radiology case reports·2026
Same author

Brain-gut axis imaging, motion correction with [ <sup>11</sup> C]-carfentanil total-body PET.

medRxiv : the preprint server for health sciences·2026
Same author

A multi-modal flow phantom for quantitative PET/Spectral CT.

bioRxiv : the preprint server for biology·2026
Same author

"Where are They Now?": A Single Institution's 10-Years Experience with an Integrated Nuclear Radiology Fellowship.

Academic radiology·2026
Same author

Correction: Acalculous cholecystitis- an imaging and therapeutic update.

Abdominal radiology (New York)·2026
Same author

Prospective exploratory pilot study of 18 F-FMISO PET/CT for assessing tumor hypoxia in soft tissue sarcomas.

Cancer imaging : the official publication of the International Cancer Imaging Society·2026

Related Experiment Video

Updated: Dec 2, 2025

Author Spotlight: Standardizing Mouse In Vivo PET Imaging with Body Conforming Molds and Automated Analysis
07:45

Author Spotlight: Standardizing Mouse In Vivo PET Imaging with Body Conforming Molds and Automated Analysis

Published on: October 25, 2024

631

Total Body PET: Why, How, What for?

Suleman Surti1, Austin R Pantel1, Joel S Karp2

  • 1Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA.

IEEE Transactions on Radiation and Plasma Medical Sciences
|November 2, 2020
PubMed
Summary
This summary is machine-generated.

New long axial field-of-view (LAFOV) PET scanners offer increased sensitivity and wider coverage for total-body imaging. Initial human studies confirm the benefits of these advanced PET-CT instruments for clinical and research applications.

Keywords:
(TB-PET)Long axial-field-of-view (LAFOV)PET-CTPennPET EXPLORERTotal-Body PETuEXPLORER

More Related Videos

Whole-body PET/MRI of Pediatric Patients: The Details That Matter
10:02

Whole-body PET/MRI of Pediatric Patients: The Details That Matter

Published on: December 19, 2017

15.0K
High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals
11:09

High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals

Published on: December 16, 2022

4.1K

Related Experiment Videos

Last Updated: Dec 2, 2025

Author Spotlight: Standardizing Mouse In Vivo PET Imaging with Body Conforming Molds and Automated Analysis
07:45

Author Spotlight: Standardizing Mouse In Vivo PET Imaging with Body Conforming Molds and Automated Analysis

Published on: October 25, 2024

631
Whole-body PET/MRI of Pediatric Patients: The Details That Matter
10:02

Whole-body PET/MRI of Pediatric Patients: The Details That Matter

Published on: December 19, 2017

15.0K
High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals
11:09

High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals

Published on: December 16, 2022

4.1K

Area of Science:

  • Medical Imaging
  • Nuclear Medicine
  • Radiological Technology

Background:

  • Positron Emission Tomography (PET) instruments have evolved with the introduction of long axial field-of-view (LAFOV) technology.
  • LAFOV enables simultaneous imaging of the entire body or significant portions (head and torso) without the need for bed translation.

Purpose of the Study:

  • To review the technological advancements leading to LAFOV PET instruments.
  • To explain the advantages of LAFOV PET-CT systems, including enhanced sensitivity and broader kinetic measurement capabilities.
  • To present initial findings from human studies utilizing LAFOV PET scanners.

Main Methods:

  • Review of LAFOV PET technology development.
  • Description of two leading LAFOV PET platforms: uEXPLORER (UC Davis) and PennPET EXPLORER (Penn).
  • Summary of initial human studies demonstrating LAFOV scanner performance.

Main Results:

  • LAFOV PET offers a dramatic increase in system sensitivity.
  • LAFOV enables kinetic measurements across multiple organs simultaneously.
  • Initial human studies confirm successful implementation and benefits of LAFOV scanners.

Conclusions:

  • LAFOV PET-CT instruments represent a significant advancement in medical imaging.
  • These systems provide enhanced capabilities for both clinical diagnostics and research applications.
  • The technology facilitates comprehensive, whole-body physiological assessments.