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Updated: Dec 2, 2025

High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals
Published on: December 16, 2022
EANM procedural guidelines for PET/CT quantitative myocardial perfusion imaging.
Roberto Sciagrà1, Mark Lubberink2,3, Fabien Hyafil4,5
1Nuclear Medicine Unit, Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, Largo Brambilla 3, 50134, Florence, Italy. roberto.sciagra@unifi.it.
Quantitative myocardial perfusion PET is increasingly used due to its advantages. This guide details high-quality procedural methods for reliable measurements and clinical data from this advanced cardiac imaging technique.
Area of Science:
- Nuclear Medicine
- Cardiovascular Imaging
- Medical Technology
Background:
- Cardiac Positron Emission Tomography (PET) use is increasing.
- Quantitative myocardial perfusion PET offers significant advantages.
- Growing scanner availability drives adoption.
Purpose of the Study:
- To provide updated guidelines on quantitative myocardial perfusion PET.
- To ensure high-quality studies and reliable measurements.
- To facilitate wider implementation of this cardiac imaging modality.
Main Methods:
- Review of current state-of-the-art in quantitative myocardial perfusion PET.
- Emphasis on procedural modalities for high-quality studies.
- Discussion of hardware, software, and new tracer developments.
Main Results:
- Detailed steps for accurate quantitative measurements.
- Highlighting the importance of a multiparametric approach.
- Stressing the need for comprehensive, clinically useful reports.
Conclusions:
- Quantitative myocardial perfusion PET is a valuable tool.
- Standardized procedures are crucial for reliable results.
- Effective reporting enhances clinical utility and implementation.
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