Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Salivary Glands and Saliva01:23

Salivary Glands and Saliva

1.7K
The salivary glands, of which there are three pairs known as the parotid, submandibular, and sublingual glands, play a crucial role in maintaining oral health and initiating the digestive process. Positioned near the ears, beneath the masseter muscle, the parotid glands secrete saliva into the oral cavity through the parotid duct of Stensen. Meanwhile, the submandibular glands, located on the floor of the mouth, secrete saliva through channels named submandibular ducts. The sublingual glands,...
1.7K
Proteomics01:33

Proteomics

9.0K
A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
9.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An Integrative Framework Identifies Cooperative Targeting of Host Pathways by Tick Salivary miRNAs.

Computational and structural biotechnology journal·2026
Same author

Leech Diversity in the Maghreb (North Africa): A Checklist and a Case Report of Parasitism on a Berber Toad (<i>Sclerophys mauritanica</i>) in Algeria.

Biology·2026
Same author

Immunomodulatory Effects of a Tick Salivary Serpin on Psoriasis-like Inflammation.

Life (Basel, Switzerland)·2026
Same author

Protease-bound structure of Ricistatin provides insights into the mechanism of action of tick salivary cystatins in the vertebrate host.

Cellular and molecular life sciences : CMLS·2023
Same author

Recent Advances in Tick Antigen Discovery and Anti-Tick Vaccine Development.

International journal of molecular sciences·2023
Same author

Editorial: Special Issue on the "Molecular Biology of Disease Vectors".

International journal of molecular sciences·2023
Same journal

Characteristics of Splenic CD8αβ<sup>+</sup> γδT Cells in Plasmodium yoelii Infection.

Parasite immunology·2026
Same journal

T-Bet Modulates Plasmodium-Specific CD4<sup>+</sup> T Cell Differentiation and Anti-Malarial Immunity During Blood-Stage Infection.

Parasite immunology·2026
Same journal

Leishmania (Leishmania) Infantum Living in Nature Secretes a Higher Concentration of Extracellular Vesicles, Suggesting Greater Infectious Potential.

Parasite immunology·2026
Same journal

IL-25 Enhances Eosinophil-Associated Inflammation in Angiostrongylus cantonensis-Infected Mice.

Parasite immunology·2026
Same journal

Potential of Postbiotics as Antiparasitic Agents.

Parasite immunology·2026
Same journal

No Evidence for Association Between ICOS (a T-Cell Co-Stimulatory Molecule) Gene Polymorphisms and Anti-MSP-1<sub>19</sub> IgG Response in Venezuelan Endemic Plasmodium vivax Malaria.

Parasite immunology·2026
See all related articles

Related Experiment Video

Updated: Dec 2, 2025

Sampling Human Indigenous Saliva Peptidome Using a Lollipop-Like Ultrafiltration Probe: Simplify and Enhance Peptide Detection for Clinical Mass Spectrometry
08:37

Sampling Human Indigenous Saliva Peptidome Using a Lollipop-Like Ultrafiltration Probe: Simplify and Enhance Peptide Detection for Clinical Mass Spectrometry

Published on: August 7, 2012

11.8K

Tick salivary gland transcriptomics and proteomics.

Larissa Almeida Martins1, Chaima Bensaoud1, Jan Kotál1,2

  • 1Institute of Parasitology, Biology Centre, Czech Academy of Sciences, České Budějovice, 37005, Czech Republic.

Parasite Immunology
|November 2, 2020
PubMed
Summary
This summary is machine-generated.

Deep sequencing reveals the tick sialome, aiding understanding of tick feeding and disease transmission. This knowledge is key for developing anti-tick vaccines and new medicines.

Keywords:
proteomesalivary glandsialometicktranscriptome

More Related Videos

Two-layered Membrane Sandwich Method for Laodelphax striatellus Saliva Collection
06:13

Two-layered Membrane Sandwich Method for Laodelphax striatellus Saliva Collection

Published on: August 27, 2021

2.6K
Multiplexed Fluorescent Microarray for Human Salivary Protein Analysis Using Polymer Microspheres and Fiber-optic Bundles
08:50

Multiplexed Fluorescent Microarray for Human Salivary Protein Analysis Using Polymer Microspheres and Fiber-optic Bundles

Published on: October 10, 2013

12.0K

Related Experiment Videos

Last Updated: Dec 2, 2025

Sampling Human Indigenous Saliva Peptidome Using a Lollipop-Like Ultrafiltration Probe: Simplify and Enhance Peptide Detection for Clinical Mass Spectrometry
08:37

Sampling Human Indigenous Saliva Peptidome Using a Lollipop-Like Ultrafiltration Probe: Simplify and Enhance Peptide Detection for Clinical Mass Spectrometry

Published on: August 7, 2012

11.8K
Two-layered Membrane Sandwich Method for Laodelphax striatellus Saliva Collection
06:13

Two-layered Membrane Sandwich Method for Laodelphax striatellus Saliva Collection

Published on: August 27, 2021

2.6K
Multiplexed Fluorescent Microarray for Human Salivary Protein Analysis Using Polymer Microspheres and Fiber-optic Bundles
08:50

Multiplexed Fluorescent Microarray for Human Salivary Protein Analysis Using Polymer Microspheres and Fiber-optic Bundles

Published on: October 10, 2013

12.0K

Area of Science:

  • Molecular Biology
  • Vector Biology
  • Parasitology

Background:

  • 'Omics' technologies identify numerous tick molecules involved in feeding and disease transmission.
  • Deep sequencing is crucial for studying vectors lacking reference genomes, like ticks.
  • The tick sialome, or salivary effector set, has vastly expanded due to advanced sequencing.

Purpose of the Study:

  • To explore the complex dynamics of the tick sialome during feeding.
  • To understand how sialome transcriptome dynamics influence tick-host-pathogen interactions.
  • To identify novel targets for controlling tick-borne diseases and discovering new drugs.

Main Methods:

  • Utilizing deep sequencing to analyze tick sialome transcriptomes.
  • Comparing transcriptomic data with previous Sanger sequencing projects.
  • Focusing on the identification and functional analysis of tick salivary effectors.

Main Results:

  • Significant expansion of the tick sialome sequence data through deep sequencing.
  • Highlighting the complexity and dynamic nature of tick feeding.
  • Establishing a foundation for understanding tick-host-pathogen interactions.

Conclusions:

  • The tick sialome plays a critical role in mediating tick feeding success.
  • Functional analysis of the sialome is essential for understanding disease transmission.
  • This research paves the way for anti-tick vaccines and novel therapeutic compounds.