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Change the channel: CysLoop receptor antagonists from nature

Guanghu Tong1, Meghan A Baker1, Ryan A Shenvi1

  • 1Department of Chemistry, Scripps Research, La Jolla, CA, USA.

Pest Management Science
|November 2, 2020
PubMed
Summary

Natural products targeting Cys-loop ligand-gated ion channels (LGICs) show promise as insecticides. Advances in chemical synthesis are making these complex natural products more accessible for development.

Keywords:
Cys-loopGABAnatural productsneuron

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