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Published on: March 28, 2025
Non-traumatic thoracic aortic emergencies: imaging diagnosis and management
Jian Ping Jen1, Akif Malik1, Gareth Lewis1
1Department of Radiology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Insights
Acute aortic syndromes, including dissection and intramural hematoma, are life-threatening emergencies. Early diagnosis via CT angiography is crucial for timely management, guiding treatment decisions for Type A and Type B aortic pathologies.
Area of Science:
- Cardiovascular Medicine
- Radiology
- Emergency Medicine
Background:
- Non-traumatic thoracic aortic emergencies, primarily acute aortic syndromes (AAS), are clinically indistinguishable and highly fatal.
- AAS encompass acute aortic dissection, intramural hematoma, and penetrating atherosclerotic ulcer, all involving aortic wall disruption.
- These conditions pose significant risks, including rupture, end-organ ischemia, and aneurysm formation, necessitating prompt diagnosis and management.
Purpose of the Study:
- To review the diagnostic computed tomography (CT) features of acute aortic syndromes.
- To highlight morphological features associated with complications in AAS.
- To outline current management strategies for different types of AAS.
Main Methods:
- Review of diagnostic imaging characteristics of AAS using paired unenhanced and electrocardiogram-gated computed tomography angiography (CTA) of the chest.
- Analysis of specific CT findings related to acute aortic dissection, intramural hematoma, and penetrating atherosclerotic ulcer.
- Correlation of imaging findings with clinical outcomes and management pathways.
Main Results:
- CTA is the recommended diagnostic modality for AAS, providing detailed morphological information.
- Specific CT features can predict complications such as rupture, ischemia, and aneurysm.
- Management strategies vary based on AAS type and complication status: Type A typically requires surgery, uncomplicated Type B receives medical therapy, and complicated Type B may involve surgery or endovascular repair.
Conclusions:
- Accurate and timely diagnosis of AAS through CTA is critical for effective patient management.
- Understanding CT features aids in identifying high-risk patients and guiding treatment decisions.
- Current management algorithms differentiate treatment based on aortic pathology type and the presence of complications.
Abstract:
The major component of non-traumatic thoracic aortic emergencies is the acute aortic syndromes. These include acute aortic dissection, intramural haematoma and penetrating atherosclerotic ulcer, grouped together because they are indistinguishable clinically and highly fatal. All three entities involve disruption to the tunica intima and media and may be complicated by rupture, end-organ ischaemia or aneurysmal transformation. Early diagnosis is vital to allow timely and appropriate management. Paired unenhanced and electrocardiogram-gated computed tomography angiography of the chest, extending more distally if required, is recommended for diagnosis. Specific computed tomography features of all three entities are reviewed, with a focus on morphological features associated with complications. Those with type A pathology are usually managed with open surgery because this has a high risk of complication. Patients with uncomplicated type B pathology are usually managed with best medical therapy whereas those with complicated type B pathology are usually offered either surgery or thoracic endovascular aortic repair. The limited evidence regarding the use of thoracic endovascular aortic repair in patients with subacute uncomplicated type B pathology is briefly discussed.
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