Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Dec 2, 2025

A Murine Orthotopic Bladder Tumor Model and Tumor Detection System
06:23

A Murine Orthotopic Bladder Tumor Model and Tumor Detection System

Published on: January 12, 2017

15.3K

Nanoparticle Enhanced Optical Biosensing Technologies for Prostate Specific Antigen Biomarker Detection.

Ahmad Usman

    IEEE Reviews in Biomedical Engineering
    |November 2, 2020
    PubMed
    Summary

    This study explores nanoparticle-enhanced optical biosensors for prostate cancer (PCa) screening. These advanced techniques aim to improve early detection accuracy using the Prostate Specific Antigen (PSA) biomarker, overcoming limitations of current methods.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Hematological parameters in atrial fibrillation: A literature review.

    World journal of cardiology·2025
    Same author

    The Association of Plasma Osmolarity With No-Reflow in Patients With ST-Segment Elevation Myocardial Infarction: A Retrospective Cohort Study.

    Cureus·2025
    Same author

    Correction: Rossi et al. Colorectal Cancer and Alcohol Consumption-Populations to Molecules. <i>Cancers</i> 2018, <i>10</i>, 38.

    Cancers·2024
    Same author

    Comparison of Access Site Complications in Primary Percutaneous Coronary Intervention (PCI) Using the Radial Versus the Femoral Approach for Complex Lesions: A Prospective Study.

    Cureus·2024
    Same author

    Achieving sustainable environment through infrastructure and energy structure developments: empirical evidence from BRICS.

    Environmental science and pollution research international·2023
    Same author

    The Outcomes of Extracorporeal Shock Wave Lithotripsy for High-Density Renal Stone on Non-Contrast Computed Tomography.

    Cureus·2021

    Area of Science:

    • Biomedical Engineering
    • Nanotechnology
    • Optical Biosensing

    Background:

    • Prostate Cancer (PCa) is a leading cause of cancer death in men.
    • Current Prostate Specific Antigen (PSA) screening lacks specificity, leading to false-positives from Benign Prostatic Hyperplasia (BPH).
    • Optical techniques are vital for cancer diagnostics, with nanoparticles (NPs) offering enhanced sensitivity and specificity.

    Purpose of the Study:

    • To review and analyze NP-enhanced optical biosensing technologies for early PCa detection.
    • To discuss challenges and research efforts in developing low-cost, point-of-care (POC) PCa diagnostic tools.
    • To highlight the potential of NP-based biosensors for accurate PSA biomarker detection.

    Main Methods:

    • Review of current state-of-the-art NP-enhanced optical biosensing techniques (absorbance, scattering, SPR, fluorescence).

    More Related Videos

    Rapid Nanoprobe Signal Enhancement by In Situ Gold Nanoparticle Synthesis
    07:30

    Rapid Nanoprobe Signal Enhancement by In Situ Gold Nanoparticle Synthesis

    Published on: March 7, 2018

    7.8K
    Author Spotlight: Engineering Molecular Tools for Disease Detection and Imaging
    04:33

    Author Spotlight: Engineering Molecular Tools for Disease Detection and Imaging

    Published on: December 8, 2023

    1.2K

    Related Experiment Videos

    Last Updated: Dec 2, 2025

    A Murine Orthotopic Bladder Tumor Model and Tumor Detection System
    06:23

    A Murine Orthotopic Bladder Tumor Model and Tumor Detection System

    Published on: January 12, 2017

    15.3K
    Rapid Nanoprobe Signal Enhancement by In Situ Gold Nanoparticle Synthesis
    07:30

    Rapid Nanoprobe Signal Enhancement by In Situ Gold Nanoparticle Synthesis

    Published on: March 7, 2018

    7.8K
    Author Spotlight: Engineering Molecular Tools for Disease Detection and Imaging
    04:33

    Author Spotlight: Engineering Molecular Tools for Disease Detection and Imaging

    Published on: December 8, 2023

    1.2K
  • Analysis of research efforts focused on improving sensitivity, specificity, and speed for PCa detection.
  • Discussion of the integration of NPs with optical biosensors for PSA biomarker quantification.

    • Main Results:

    • NP incorporation significantly enhances the performance of optical biosensors for cancer diagnostics.
    • These technologies show promise for highly specific and sensitive detection of the PSA biomarker.
    • Advancements are paving the way for low-cost, POC diagnostic solutions for early PCa detection.

    Conclusions:

    • NP-enhanced optical biosensing represents a significant advancement in PCa early detection strategies.
    • Addressing current challenges can lead to the widespread adoption of sensitive and specific POC diagnostic tools.
    • Further research is crucial for realizing the full potential of these technologies in clinical settings.