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Updated: Dec 2, 2025
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Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
Published on: December 14, 2020
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Dysphonia and reflux in children: A systematic review
Jeyasakthy Saniasiaya1, Jeyanthi Kulasegarah2
1Department of Otorhinolaryngology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.
International Journal of Pediatric Otorhinolaryngology
|November 2, 2020
Summary
Reflux, including laryngopharyngeal and gastroesophageal reflux, is strongly linked to childhood dysphonia. Treatment shows promise, with 68% of children improving after 4.5 months.
Area of Science:
- Otolaryngology
- Pediatric Gastroenterology
- Speech-Language Pathology
Background:
- Dysphonia in children is a significant concern.
- Gastroesophageal reflux (GER) and laryngopharyngeal reflux (LPR) are potential contributing factors to voice disorders.
Purpose of the Study:
- To evaluate the relationship between laryngopharyngeal reflux (LPR) or gastroesophageal reflux (GER) and dysphonia in pediatric patients.
Main Methods:
- A comprehensive literature search was performed across PubMed, Scopus, and Embase databases.
- The search encompassed studies published from January 1990 to March 2020, using keywords such as 'voice disorders,' 'laryngopharyngeal reflux,' and 'gastroesophageal reflux.'
- Five clinical studies, predominantly of Level III evidence, were selected for review, totaling 606 pediatric patients.
Main Results:
- A strong association between reflux (GER/LPR) and dysphonia was observed in all included studies.
- 24-hour pH monitoring confirmed reflux in 69% of cases.
- Common laryngoscopic findings included interarytenoid erythema/edema (32/38), vocal cord erythema/edema (160/231), and postglottic edema (141/337). Vocal cord nodules were present in 28% of patients.
Conclusions:
- There is substantial evidence supporting a strong link between reflux and dysphonia in children.
- Key laryngoscopic indicators of reflux include interarytenoid and vocal cord erythema/edema, and postglottic edema.
- Treatment interventions demonstrated positive outcomes, with significant symptom improvement in pediatric patients.
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