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Cancer-related fatigue: Systematic reviews and meta-analyses of mind-body intervention

Huda Anshasi1, Muayyad Ahmad2

  • 1Nursing Department, Fatima College of Health Science, Abu Dhabi, United Arab Emirates.

Palliative & Supportive Care
|November 3, 2020
PubMed
Abstract

Insights

This study assessed the quality of systematic reviews on mind-body interventions for cancer fatigue. Most reviews had methodological weaknesses, highlighting the need for stronger research practices and adherence to reporting guidelines.

Area of Science:

  • Oncology
  • Evidence-Based Medicine
  • Systematic Reviews

Background:

  • Cancer-related fatigue is a common and debilitating symptom.
  • Mind-body interventions (MBIs) show promise for managing cancer-related fatigue.
  • The methodological quality of existing systematic reviews on MBIs for cancer fatigue needs evaluation.

Purpose of the Study:

  • To evaluate the methodological quality of systematic reviews and meta-analyses on mind-body interventions for cancer-related fatigue.
  • To identify common methodological weaknesses in these reviews.
  • To provide recommendations for improving the quality of future systematic reviews.

Main Methods:

  • A comprehensive literature search was conducted for systematic reviews and meta-analyses published between January 2008 and December 2019.
  • Two independent reviewers selected studies, extracted data, and assessed methodological quality using the Assessing the Methodological Quality of Systematic Reviews (AMSTAR) tool.
  • Sixteen systematic reviews were included in the final analysis.

Main Results:

  • The methodological quality of the 16 included systematic reviews ranged from moderate to high on the 11-point AMSTAR scale.
  • Common weaknesses included the absence of a list of excluded studies (93.8%) and a priori protocols (87.5%).
  • A significant majority of reviews (81.3%) did not search the gray literature.

Conclusions:

  • There is a need for higher methodological quality in systematic reviews addressing mind-body interventions for cancer-related fatigue.
  • Future systematic reviews should incorporate a priori designs, include a list of excluded studies, and consider gray literature.
  • Adherence to guidelines like the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) is recommended.
Keywords:
AMSTARCancer-related fatigueMeta-analysesMind–body interventionsSystematic reviews

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