Co-Cr mixed spinel oxide nanodots anchored on nitrogen-doped carbon nanotubes as catalytic electrode for hydrogen...

Hydrogen peroxide (H₂O₂) is a significant biomarker in physiological processes. Abnormal levels of H₂O₂ are considered to be closely related to some acute diseases. Therefore, it is important to monitor the H₂O₂ levels in bio-samples. Herein, we present a novel non-enzymatic electrochemical H₂O₂ sensor based on the excellent electrocatalytic performance of a composite comprising Zn-Cr-Co ternary spinel metal oxide nanodots (ZnCrCoO₄) anchored on the surface of nitrogen-doped carbon nanotubes (NCNTs), denoted as ZnCrCoO₄/NCNTs, toward H₂O₂ reduction. ZnCrCoO₄/NCNTs were synthesized using a facile one-pot hydrothermal strategy. The enhanced electrocatalytic performance of ZnCrCoO₄ is resulted from the partial substitution of Co in spinel zinc cobaltate (ZnCo₂O₄) with Cr, which modifies the CoO electronic structure and enhances electroconductivity. The ZnCrCoO₄/NCNTs-based H₂O₂ sensor exhibited a wide quantitative detection range from 1 to 7330 μM with a detection limit of 1 μM. The sensor showed excellent reproducibility and selectivity for H₂O₂ sensing. In addition, remarkable recoveries were obtained for H₂O₂-spiked fish serum samples. These results demonstrated that the as-developed sensor has a great potential in monitoring H₂O₂ levels in practical applications.