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Related Concept Videos

Genomics02:02

Genomics

39.0K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
39.0K
Genome Annotation and Assembly03:36

Genome Annotation and Assembly

20.0K
The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.
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Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

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Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
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Comparing Mitochondrial, Chloroplast, and Prokaryotic Genomes02:16

Comparing Mitochondrial, Chloroplast, and Prokaryotic Genomes

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The present-day mitochondrial and chloroplast genomes have retained some of the characteristics of their ancestral prokaryotes and also have acquired new attributes during their evolution within eukaryotic cells. Like prokaryotic genomes, mitochondrial and chloroplast genomes neither bind with histone-like proteins nor show complex packaging into chromosome-like structures, as observed in eukaryotes. Unlike mitotic cell divisions observed in eukaryotic cells, mitochondria and chloroplasts...
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Genome Size and the Evolution of New Genes03:21

Genome Size and the Evolution of New Genes

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Next-generation Sequencing03:00

Next-generation Sequencing

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The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features....
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Related Experiment Video

Updated: Dec 2, 2025

Novel Sequence Discovery by Subtractive Genomics
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Novel Sequence Discovery by Subtractive Genomics

Published on: January 25, 2019

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Author Correction: Plant pan-genomes are the new reference.

Philipp E Bayer1, Agnieszka A Golicz2, Armin Scheben3

  • 1School of Biological Sciences and Institute of Agriculture, University of Western Australia, Perth, Western Australia, Australia.

Nature Plants
|November 3, 2020
PubMed
Summary

This study has been updated. Please refer to the amendment at the top of the paper for the latest information and findings.

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Area of Science:

  • Not specified

Context:

  • An amendment to this paper has been published.

Purpose:

  • To inform readers about a published amendment.

Summary:

  • The original paper has been amended.
  • The amendment is accessible via a link at the top of the paper.

Impact:

  • Ensures readers access the most current version of the research.
  • Facilitates accurate understanding of the study's findings.