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Integrated Single-Cell Atlases Reveal an Oral SARS-CoV-2 Infection and Transmission Axis
Medrxiv : the Preprint Server for Health Sciences
|November 3, 2020
Summary
The oral cavity, including salivary glands, is a key site for SARS-CoV-2 infection. Saliva from infected individuals contains the virus and correlates with COVID-19 symptoms, suggesting its role in transmission.
Area of Science:
- Oral biology
- Virology
- Immunology
Background:
- The role of the oral cavity in COVID-19 pathogenesis remains unclear despite observed infection signs.
- Understanding oral viral dynamics is crucial for managing SARS-CoV-2 (COVID-19) infection.
Conclusions:
- The oral cavity is a significant site for SARS-CoV-2 infection.
- Saliva plays a role in SARS-CoV-2 transmission.
- Oral epithelial cells are susceptible to SARS-CoV-2 infection and can harbor the virus.
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