Related Experiment Video

Updated: Dec 2, 2025

Construction of Cyclic Cell-Penetrating Peptides for Enhanced Penetration of Biological Barriers
10:12

Construction of Cyclic Cell-Penetrating Peptides for Enhanced Penetration of Biological Barriers

Published on: September 19, 2022

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[Use of complex preparations of cationic peptides in the treatment of acute pharyngitis]

A I Asmanov1, N D Pivneva1

  • 1Veltischev Research and Clinical Institute for Pediatrics of the Pirogov Russian National Research Medical University, Moscow, Russia.

Vestnik Otorinolaringologii
|November 3, 2020
PubMed

Insights

This study found the drug Doritricin to be effective and safe for treating acute viral pharyngitis in children. Doritricin offers a rapid and significant therapeutic effect in pediatric patients.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Pharmacology

Background:

  • Acute respiratory infections are a leading cause of illness in children.
  • Pharyngitis is commonly treated with antibacterials, despite often being viral.
  • Cationic peptides offer broad-spectrum antimicrobial activity.

Purpose of the Study:

  • To evaluate the efficacy and safety of Doritricin for treating childhood acute viral pharyngitis.

Main Methods:

  • A study involving 120 pediatric patients aged 6-18 with viral pharyngitis.
  • Treatment administered between September 2019 and January 2020.
  • The drug "Doritricin" was used for treatment.

Main Results:

  • The drug "Doritricin" demonstrated a fast and high therapeutic effect.
  • The results indicate significant efficacy in pediatric practice.

Conclusions:

  • "Doritricin" is an effective and safe treatment option for acute viral pharyngitis in children.
  • The study supports the use of "Doritricin" in pediatric care for pharyngitis.

Keywords:
cationic peptideschildren oropharynxpharyngitissore throattopical therapy

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