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Subcoronary Ross/Ross-Konno operation in children and young adults: initial single-centre experience
Peter Murin1, Viktoria H M Weixler1, Jasmin Moulla-Zeghouane1
1Department of Congenital Heart Surgery - Pediatric Heart Surgery, German Heart Center Berlin, Berlin, Germany.
Insights
The modified subcoronary Ross/Ross-Konno operation shows excellent outcomes in children and young adults. However, mortality and morbidity remain significant concerns for infants undergoing this procedure.
Area of Science:
- Pediatric Cardiac Surgery
- Aortic Valve Repair
- Congenital Heart Disease
Background:
- The Ross/Ross-Konno operation is a complex procedure for aortic valve disease.
- Modified techniques aim to improve outcomes in pediatric and young adult populations.
- Evaluating the long-term results of modified subcoronary Ross/Ross-Konno procedures is crucial.
Purpose of the Study:
- To assess the outcomes of the modified subcoronary Ross/Ross-Konno operation in pediatric and young adult patients.
- To analyze survival rates, morbidity, need for reintervention, aortic valve function, and aortic root dimensions.
- To identify specific risks and benefits in different age groups, particularly infants.
Main Methods:
- A retrospective analysis of 50 patients (median age 6.3 years) who underwent the modified subcoronary Ross/Ross-Konno operation between January 2013 and January 2019.
- Evaluation of survival, morbidity, reoperations, aortic valve function, and aortic root dimensions.
- Follow-up data analyzed for early and late outcomes, including reinterventions and valve function.
Main Results:
- Overall 5-year survival was 95%, with 1 early and 1 late death, both in the infant group.
- Freedom from reoperation on the autograft and RV-PA conduit at 5 years was 94% and 97%, respectively.
- 97% freedom from >mild aortic regurgitation at 5 years, with normal aortic root dimensions and excellent left ventricular function in most survivors.
Conclusions:
- The modified subcoronary Ross/Ross-Konno operation demonstrates excellent outcomes in children and young adults.
- Mortality and morbidity in infants undergoing this procedure remain significant.
- The technique is reproducible and offers advantages over prosthetic techniques that may impede somatic growth.
Objectives:
We sought to evaluate the outcome after modified subcoronary Ross/Ross-Konno operation in children and young adults.
Methods:
Between January 2013 and January 2019, a total of 50 patients with median age of 6.3 years (range 0.02-36.5 years, 58% males), including 10 infants (20%), received modified subcoronary Ross/Ross-Konno operation at our institution. Survival, morbidity, reinterventions, aortic valve function and aortic root dimensions were analysed.
Results:
At a median follow-up of 31.2 months (range 14.4-51 months), there were 1 early death and 1 late death, both in the infant group. The overall survival at 5 years after the operation was 95%. Two patients needed aortic valve replacement, 11 and 15 months after their Ross operation. At 5 years, freedoms from reoperation on the autograft and on the right ventricle to pulmonary artery conduit were 94% and 97%, respectively. Freedom from aortic valve regurgitation greater than mild was 97% at 5 years. Median dimensions of the aortic root at all levels remained in normal range at last visit. Forty-four patients (95%) were in New York Heart Association class I with normal left ventricular function.
Conclusions:
The initial experience with the subcoronary Ross/Ross-Konno operation in children and young adults showed excellent outcome. The mortality and morbidity among infants remain significant. The described technique is reproducible and might be advantageous in situations when prosthetic supporting techniques interfere with somatic growth.
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