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IgA vasculitis in a patient with ulcerative colitis under infliximab: drug-induced or genetic?
Jun Urushikubo1, Shunichi Yanai2, Shotaro Nakamura2
1Division of Gastroenterology, Department of Internal Medicine, School of Medicine, Iwate Medical University, Morioka, Japan. urujun50@gmail.com.
Abstract:
We present the case of a 17-year-old male patient with ulcerative colitis (UC) under infliximab therapy and a family history of IgA vasculitis (IgAV). During a maintenance infliximab session, he developed palpable purpura, abdominal pain, and hematochezia. Computed tomography and endoscopy revealed findings compatible with gastrointestinal manifestations of IgAV. He was successfully treated by intravenous prednisolone and did not develop recurrence of IgAV during subsequent infliximab infusions.
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