Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Contractile Ring02:15

The Contractile Ring

6.9K
Contractile rings are composed of microfilaments and are responsible for separating the daughter cells during cytokinesis. Contractile ring assembly proceeds along with other cell cycle events; however, very few mechanistic details are known about the timing and coordination of the contractile rings with the cell cycle.
A small GTPase, RhoA, controls the function and assembly of the contractile ring. RhoA belongs to the Ras superfamily of proteins. The activation of formins by RhoA promotes...
6.9K
RNA Structure01:23

RNA Structure

77.8K
Overview
The basic structure of RNA consists of a five-carbon sugar and one of four nitrogenous bases. Although most RNA is single-stranded, it can form complex secondary and tertiary structures. Such structures play essential roles in the regulation of transcription and translation.
Different Types of RNA Have the Same Basic Structure
There are three main types of ribonucleic acid (RNA): messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). All three RNA types consist of a...
77.8K
RNA Structure01:19

RNA Structure

6.4K
The basic structure of RNA consists of a string of ribonucleotides attached by phosphodiester bonds. Although most RNA is single-stranded, it can form complex secondary and tertiary structures. Such structures play essential roles in the regulation of transcription and translation.
Different Types of RNA Have the Same Basic Structure
There are three main types of ribonucleic acid (RNA) involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). All three...
6.4K
Nucleic Acid Structure01:25

Nucleic Acid Structure

8.0K
The pentose sugar in DNA is deoxyribose, while in RNA the pentose sugar is ribose. The difference between the sugars is the presence of the hydroxyl group on the ribose's second carbon and a hydrogen on the deoxyribose's second carbon. The phosphate residue attaches to the hydroxyl group of the 5′ carbon of one sugar and the hydroxyl group of the 3′ carbon of the sugar of the next nucleotide, which forms  a 5′ to 3′ phosphodiester linkage.
DNA Structure
DNA...
8.0K
Conserved Binding Sites01:49

Conserved Binding Sites

4.9K
Many proteins’ biological role depends on their interactions with their ligands, small molecules that bind to specific locations on the protein known as ligand-binding sites. Ligand-binding sites are often conserved among homologous proteins as these sites are critical for protein function.
Binding sites are often located in large pockets, and if their location on a protein’s surface is unknown, it can be predicted using various approaches. The energetic method computationally...
4.9K
DNA Helicases00:55

DNA Helicases

23.4K
DNA unwinding helicase enzymes are a type of motor protein. Motor proteins can translocate along filaments or polymers using energy generated from ATP hydrolysis. Helicases are involved in all the important cellular processes where DNA unwinding is required, such as DNA replication, repair, recombination, and transcription. They are present in all living organisms, but vary in their structure, function, and mechanism of action. For example, in prokaryotes, DnaB helicase binds and translocates...
23.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Thermodynamic-Kinetic Tailored Photothermal-Responsive Molecular Switching for Extracellular Vesicle Manipulation.

ACS nano·2026
Same author

Unraveling hidden species diversity of talpid moles using phylogenomics and skull-based deep learning.

Communications biology·2026
Same author

Linear Force Scaling in Kinesin-Driven Microtubule Swarms Revealed by Electromagnetic Tweezers.

ACS nano·2026
Same author

Highly efficient genome editing using CRISPR/Cas9 ribonucleoprotein in the marine oleaginous diatom Fistulifera solaris.

Scientific reports·2026
Same author

Polyethylene terephthalate microplastics impair erectile function through macrophage mediated cGAS-STING ferroptosis.

iScience·2026
Same author

DeepMLP: A Proteomics-Driven Deep Learning Framework for Identifying Mis-Localized Proteins across Pan-Cancer.

Journal of chemical information and modeling·2025

Related Experiment Video

Updated: Dec 2, 2025

Stable DNA Motifs, 1D and 2D Nanostructures Constructed from Small Circular DNA Molecules
09:32

Stable DNA Motifs, 1D and 2D Nanostructures Constructed from Small Circular DNA Molecules

Published on: April 12, 2019

6.9K

DNA Ring Motif with Flexible Joints.

Shiyun Liu1, Satoshi Murata1, Ibuki Kawamata1,2

  • 1Department of Robotics, Graduate School of Engineering, Tohoku University, Sendai 980-8579, Japan.

Micromachines
|November 4, 2020
PubMed
Summary

Researchers developed a flexible DNA origami ring motif for programmable self-assembly. This novel module allows for adjustable shapes and connections, enabling the creation of functional molecular devices.

Keywords:
DNA nanotechnologyDNA origamimolecular robotics

More Related Videos

Design and Synthesis of a Reconfigurable DNA Accordion Rack
07:44

Design and Synthesis of a Reconfigurable DNA Accordion Rack

Published on: August 15, 2018

7.3K
DNA Nanotubes as a Versatile Tool to Study Semiflexible Polymers
08:00

DNA Nanotubes as a Versatile Tool to Study Semiflexible Polymers

Published on: October 25, 2017

7.1K

Related Experiment Videos

Last Updated: Dec 2, 2025

Stable DNA Motifs, 1D and 2D Nanostructures Constructed from Small Circular DNA Molecules
09:32

Stable DNA Motifs, 1D and 2D Nanostructures Constructed from Small Circular DNA Molecules

Published on: April 12, 2019

6.9K
Design and Synthesis of a Reconfigurable DNA Accordion Rack
07:44

Design and Synthesis of a Reconfigurable DNA Accordion Rack

Published on: August 15, 2018

7.3K
DNA Nanotubes as a Versatile Tool to Study Semiflexible Polymers
08:00

DNA Nanotubes as a Versatile Tool to Study Semiflexible Polymers

Published on: October 25, 2017

7.1K

Area of Science:

  • Nanotechnology
  • Molecular Biology
  • Materials Science

Background:

  • DNA origami has advanced DNA nanostructure complexity and function.
  • Existing DNA nanostructures have limitations in flexibility and programmability.

Purpose of the Study:

  • To develop a novel, flexible multi-joint ring motif using DNA origami technology.
  • To enable programmable self-assembly of DNA nanostructures with adjustable shapes.

Main Methods:

  • Design of a self-assembling module with flexible joints and self-complementary connection sequences.
  • Utilizing DNA origami principles for motif construction.
  • Evaluating various self-assembly patterns and shape configurations.

Main Results:

  • Successful production of the flexible multi-joint ring motif.
  • Demonstration of motif's ability to connect and form various shapes by adjusting joints and segments.
  • Programmable self-assembly of the motif was achieved.

Conclusions:

  • The flexible multi-joint ring motif offers a new approach for designing functional molecular devices.
  • This module enhances the versatility and programmability of DNA nanostructures.
  • The technology facilitates the creation of complex, shape-shifting molecular architectures.