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Hemodialysis vascular access affects heart function and outcomes: Tips for choosing the right access for the
Jan Malik1, Carlo Lomonte2, Joris Rotmans3
1Third Department of Internal Medicine, General University Hospital, First Faculty of Medicine, Charles University, Prague, Czech Republic.
Insights
Arteriovenous (AV) fistula, crucial for hemodialysis survival, can impact heart function. This review examines cardiovascular hemodynamics in dialysis patients, focusing on AV access effects and management strategies for optimal cardiac health.
Area of Science:
- Nephrology
- Cardiology
- Vascular Surgery
Background:
- Chronic kidney disease (CKD) significantly increases cardiovascular morbidity and mortality.
- Arteriovenous (AV) fistula offers superior outcomes for hemodialysis vascular access but can affect cardiac function.
- Understanding the cardiovascular impact of AV access is critical for managing dialysis patients.
Purpose of the Study:
- To review the cardiovascular hemodynamics in dialysis patients related to AV access.
- To explore the effects of AV access on heart function, including high-output heart failure and pulmonary hypertension.
- To provide guidance on vascular access selection and management in CKD patients with cardiac conditions.
Main Methods:
- Literature review focusing on cardiovascular hemodynamics in dialysis patients.
- Analysis of AV access impact on cardiac function and clinical status.
- Examination of alternative dialysis modalities and vascular access considerations.
Main Results:
- AV access, while beneficial for survival, can lead to adverse cardiac events like high-output heart failure.
- Peritoneal dialysis may be preferable in severe heart failure cases.
- Management strategies for AV access in kidney transplant recipients and patients switching modalities are discussed.
Conclusions:
- Careful consideration of AV access type and management is essential for dialysis patients, especially those with pre-existing cardiac conditions.
- Individualized vascular access selection is crucial for optimizing cardiac health in CKD patients.
- The interplay between vascular access, cardiac health, and interventions like cardiac surgery requires integrated management.
Abstract:
Chronic kidney disease is associated with increased cardiovascular morbidity and mortality. A well-functioning vascular access is associated with improved survival and among the available types of vascular access the arterio-venous (AV) fistula is the one associated with the best outcomes. However, AV access may affect heart function and, in some patients, could worsen the clinical status. This review article focuses on the specific cardiovascular hemodynamics of dialysis patients and how it is affected by the AV access; the effects of an excessive increase in AV access flow, leading to high-output heart failure; congestive heart failure in CKD patients and the contraindications to AV access; pulmonary hypertension. In severe heart failure, peritoneal dialysis (PD) might be the better choice for cardiac health, but if contraindicated suggestions for vascular access selection are provided based on the individual clinical presentation. Management of the AV access after kidney transplantation is also addressed, considering the cardiovascular benefit of AV access ligation compared to the advantage of having a functioning AVF as backup in case of allograft failure. In PD patients, who need to switch to hemodialysis, vascular access should be created timely. The influence of AV access in patients undergoing cardiac surgery for valvular or ischemic heart disease is also addressed. Cardiovascular implantable electronic devices are increasingly implanted in dialysis patients, but when doing so, the type and location of vascular access should be considered.
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