Biochemical Markers in COVID-19 in Multan

Area of Science:

• Medical Research
• Infectious Diseases
• Clinical Biochemistry

Background:

• COVID-19 presents with diverse clinical manifestations.
• Understanding clinical and biochemical profiles is crucial for patient management.

Purpose of the Study:

• To determine clinical features and biochemical markers in COVID-19 patients at a tertiary care hospital in Multan, Pakistan.
• To explore associations between clinical symptoms and biochemical markers.

Main Methods:

• A descriptive cross-sectional study was conducted.
• Sixty-three COVID-19 patients of all ages were included.
• Clinical features and biochemical markers (serum albumin, ferritin, AST, LDH, CRP, urea) were analyzed.

Main Results:

• The majority of patients (66.7%) were aged 13-45 years, with a mean age of 41.39 years.
• Males constituted 76.2% of the study population.
• Key biochemical markers showed median values: ferritin 176.5 ng/ml, LDH 284 IU/L, albumin 42 g/L, AST 28 U/L, CRP 3.9 mg/L, and urea 4.25 mmol/L.

Conclusions:

• COVID-19 patients in Pakistan exhibit variable clinical features.
• Serum ferritin is a potential biochemical marker for aiding COVID-19 diagnosis.
• Further research is needed to elucidate the full spectrum of clinical and biochemical findings.