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Updated: Dec 2, 2025

Stable Isotope In-Vivo Labeling for Mass-Spectrometry Identification of Paternal Metabolites Transferred from Sperm to Oocyte During Fertilization

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Published on: June 17, 2025

Thermal transgenerational effects remain after two generations.

Who-Seung Lee^1,2,3, Santiago Salinas⁴, Young-Rog Lee²

¹Center for Stock Assessment Research University of California Santa Cruz CA USA.

Ecology and Evolution

|November 4, 2020

Summary

This summary is machine-generated.

Transgenerational plasticity (TGP) effects in fish diminish across generations. Experiencing novel temperatures accelerates this decline, highlighting the need for further research into TGP dynamics.

Keywords:

Cyprinodon variegatus grandparent growth rate multigeneration temperature transgenerational plasticity

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Published on: July 29, 2019

Area of Science:

Evolutionary biology
Ecology
Genetics

Background:

Transgenerational plasticity (TGP) allows organisms to adapt to changing environments across generations.
Understanding the persistence of parental environmental effects beyond offspring is crucial.
Previous studies explored TGP evolution, but multigenerational effects remain less clear.

Purpose of the Study:

To investigate the multigenerational strength of thermal TGP in a cyprinodontid fish.
To determine if TGP strength declines or accumulates across generations.
To assess how novel temperature experiences impact TGP persistence.

Main Methods:

Experimental manipulation of temperature across multiple generations (F0, F1, F2) in fish.
Analysis of juvenile growth and egg diameter as indicators of TGP.
Comparison of TGP strength between control and novel temperature exposure groups.

Main Results:

A significant interaction between F1 and F2 temperatures affected juvenile growth, but egg diameter was not influenced.
TGP strength was similar between parental (F0) and first-generation offspring (F1).
TGP strength declined in subsequent generations (F2 onwards), with novel temperature experience accelerating this decline.

Conclusions:

The strength of transgenerational plasticity diminishes over successive generations.
Exposure to novel environmental conditions can hasten the decline of TGP.
Further theoretical and empirical work is necessary to fully understand multigenerational TGP dynamics.