Related Experiment Video
Updated: Dec 2, 2025
Noninvasive Determination of Vortex Formation Time Using Transesophageal Echocardiography During Cardiac Surgery
Published on: November 28, 2018
Risk factors of chronic left ventricular dysfunction after cardiac valve surgery
Xingli Fan1, Yangfeng Tang1, Guanxin Zhang1
1Department of Cardiovascular Surgery, Changhai Hospital, Naval Medical University, Shanghai, China.
Insights
Chronic left ventricular dysfunction (LVD) after heart valve surgery is linked to enlarged left ventricular diameter, coronary artery disease, atrial fibrillation, and pulmonary hypertension. These factors increase the risk of developing LVD post-operation.
Area of Science:
- Cardiology
- Cardiac Surgery
- Cardiovascular Research
Background:
- Cardiac valve surgery is crucial for treating valvular heart disease.
- Left ventricular dysfunction (LVD) is a potential complication following these procedures.
- Identifying risk factors for LVD is essential for improving patient outcomes.
Purpose of the Study:
- To investigate the risk factors associated with chronic left ventricular dysfunction (LVD) after cardiac valve surgery.
- To identify specific preoperative clinical and echocardiographic parameters that predict postoperative LVD.
Main Methods:
- Retrospective analysis of 860 patients undergoing heart valve surgery.
- Patients were categorized into LVD (LVEF <40%) and control (LVEF ≥40%) groups at 6 months post-surgery.
- Logistic regression analysis was employed to determine risk factors for postoperative LVD.
Main Results:
- 126 patients developed LVD post-surgery.
- Significant differences were observed in preoperative coronary artery disease, atrial fibrillation, pulmonary hypertension, NYHA classification, LVEDD, and LVESD between groups.
- Preoperative LVEDD >55 mm, LVESD >40 mm, atrial fibrillation, pulmonary hypertension, NYHA III-IV, and coronary artery disease were identified as significant risk factors for LVD.
Conclusions:
- Preoperative left ventricular dimensions (LVEDD and LVESD) are critical indicators of LVD risk.
- Existing comorbidities such as coronary artery disease, atrial fibrillation, and pulmonary hypertension significantly elevate the risk of postoperative LVD.
- Patients with NYHA class III-IV also face a higher likelihood of developing chronic LVD after valve surgery.
Background:
To analyze the risk factors of chronic left ventricular dysfunction (LVD) after cardiac valve surgery.
Methods:
A retrospective analysis of 860 patients who underwent heart valve surgery in our center from January 2017 to December 2018, including 650 males and 210 females, aged 58±5.8 years. Inclusion criteria: (I) the patient was clinically diagnosed with heart valve disease and met the surgical indications for mitral valve replacement (MVR), mitral valve repair (MVP), aortic valve replacement (AVR) and double valve replacement (DVR); (II) if atrial fibrillation, coronary artery disease, and tricuspid regurgitation are combined before surgery, radiofrequency ablation, coronary bypass and tricuspid angioplasty were performed contemporarily. Exclusion criteria: (I) preoperative LVEF <50%; (II) aortic dissection underwent Bentall and right heart valve replacement procedures; (III) cardiopulmonary resuscitation and death during perioperative period and 6 months after operation; (IV) postoperative CRRT, IABP, or ECMO assistance; (V) postoperative cardiac dysfunction due to valvular dysfunction, perivalvular leak, or infective endocarditis. Patients were divided into LVD group (LVEF <40%) and control group (LVEF ≥40%) based on cardiac LVEF at 6 months after surgery. Logistic regression was used to analyze the risk factors of postoperative LVD.
Results:
There were 126 cases in LVD group and 734 cases in control group. There were significant differences in preoperative coronary artery disease, atrial fibrillation, pulmonary hypertension, NYHA classification, left ventricular end diastolic diameter (LVEDD), and left ventricular end systolic diameter (LVESD) between the two groups (P<0.05). The differences in the changes of LVEDD and LVESD before and after operation between the two groups were statistically significant (P<0.05). Logistic regression analysis showed that preoperative LVEDD >55 mm, preoperative LVESD >40 mm, preoperative combined atrial fibrillation, preoperative combined pulmonary hypertension, preoperative NYHA III-IV, and preoperative combined coronary artery disease were the risks of postoperative chronic LVD.
Conclusions:
The left ventricular diameter, preoperative coronary artery disease, NYHA III-IV, preoperative atrial fibrillation, and preoperative pulmonary hypertension are risk factors for chronic LVD after heart valve surgery.
More Related Videos
14:35Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs
Published on: April 17, 2021
08:49Author Spotlight: Enhancing Graft Viability Assessment Through Quantitative Metrics and Innovative Reservoir Systems
Published on: August 2, 2024
Related Concept Videos
01:22Mitral Stenosis I: Introduction
01:20Mitral Regurgitation I: Introduction
01:27Heart Failure I: Introduction
01:26Imbalances in Cardiac Output
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
01:25Aortic Regurgitation III: Medical Management
01:28Cardiomyopathy VII: Pre and Post Operative Nursing Management