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Updated: Dec 2, 2025

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Electromagnetic Navigation Transthoracic Nodule Localization for Minimally Invasive Thoracic Surgery
Published on: May 4, 2022
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A new method for accurately localizing and resecting pulmonary nodules
Gongming Wang1, Yongyong Lin1, Lie Zheng1
1Department of Thoracic Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.
Journal of Thoracic Disease
|November 4, 2020
Summary
This study introduces a new method for precisely locating and resecting small lung nodules using indocyanine green (ICG) injection guided by electromagnetic navigation bronchoscopy. This technique improves accuracy and safety in minimally invasive lung cancer surgery.
Area of Science:
- Thoracic Surgery
- Pulmonology
- Medical Imaging
Background:
- Low-dose CT screening increases early lung cancer detection, leading to more small pulmonary nodules.
- Resecting small, deep, non-solid lung nodules via video-assisted thoracoscopic surgery presents significant surgical challenges.
- Current localization methods have limitations, including patient immobility requirements and potential complications.
Observation:
- Traditional methods like CT-guided hook-wire or dye injection require patient activity restriction post-localization.
- Previous electromagnetic navigation bronchoscopy techniques used melamine dye, which has associated drawbacks.
- This case introduces indocyanine green (ICG) as a novel localization agent.
Findings:
- Indocyanine green (ICG) was injected under electromagnetic navigation bronchoscopy guidance for accurate pulmonary nodule localization.
- Small pulmonary nodules were successfully resected under fluoroscopic guidance following ICG localization.
- This new method offers a potentially more effective approach to nodule localization.
Implications:
- This technique may enhance the precision and safety of minimally invasive resection for small pulmonary nodules.
- It could reduce complications associated with traditional localization methods.
- Further research may validate ICG as a superior agent for preoperative nodule localization in lung cancer surgery.

