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Transient Middle Cerebral Artery Occlusion Model of Neonatal Stroke in P10 Rats
Published on: April 21, 2017
Acute Ischemic Stroke due to Internal Carotid Artery Dissection in a 10-Year-Old Child
Saori Otake1, Yosuke Tajima1, Michihiro Hayasaka1
1Department of Neurosurgery, Kimitsu Chuo Hospital, Kisarazu City, Chiba, Japan.
Insights
Pediatric ischemic stroke caused by internal carotid artery dissection (ICAD) can significantly improve with prompt diagnosis and treatment. Early MRI is vital for identifying ICAD in children with neurological deficits, even without trauma history.
Area of Science:
- Pediatric Neurology
- Vascular Neurology
- Neuroradiology
Background:
- Internal carotid artery dissection (ICAD) is a rare but serious cause of stroke in children.
- Unexplained neurological deficits in children warrant thorough investigation for underlying vascular causes.
- Prompt diagnosis and treatment of ICAD are critical for favorable neurological outcomes.
Abstract:
A 10-year-old girl was transferred to our hospital with left hemiparesis. Diffusion-weighted magnetic resonance imaging (MRI) of the brain showed a signal lesion in the right posterior limb of the internal capsule and magnetic resonance angiography showed poor visualization of the right internal carotid artery (ICA), and a defect area was present in a part of the supraclinoid portion of the right ICA. Based on the clinical and radiological findings, the patient was diagnosed with ischemic stroke due to right ICA dissection (ICAD). She received 5 days of intravenous argatroban followed by oral aspirin. A month later, her hemiparesis markedly improved. As early diagnosis of ICAD is crucial for prompt treatment in children with unexplained gross neurologic abnormalities, this disease should be suspected and MRI should be performed even without a history of blunt trauma to the head and neck.
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