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Updated: Dec 2, 2025

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Catheter ablation for atrial fibrillation in a low-volume center using contemporary technology
Julian Cheong Kiat Tay1, Xinzhe James Cai1, Jing Lin1
1Department of Cardiology, Changi General Hospital (CGH), Singapore.
Insights
Catheter ablation for atrial fibrillation (AF) in low-volume centers demonstrates comparable safety and efficacy to high-volume centers. Contemporary technologies ensure similar recurrence and complication rates for both paroxysmal and persistent AF.
Area of Science:
- Cardiology
- Electrophysiology
Background:
- Catheter ablation for atrial fibrillation (AF) is common globally.
- Concerns exist regarding lower success rates and higher complications in low-volume centers.
- This study evaluates AF catheter ablation safety and efficacy in a low-volume setting.
Purpose of the Study:
- To assess the safety and effectiveness of AF catheter ablation at a low-volume center.
- To compare outcomes with those reported from high-volume centers.
- To determine if contemporary technologies mitigate potential disadvantages of low-volume procedures.
Main Methods:
- A retrospective study of 71 consecutive patients undergoing their first AF catheter ablation.
- Primary outcome: AF recurrence rate at one year.
- Secondary outcomes: periprocedural complications, post-ablation hospitalizations, and repeat ablations.
Main Results:
- One-year AF recurrence was 19.5% for paroxysmal AF and 23.8% for persistent AF.
- Procedural and ablation times were longer for persistent AF.
- No significant differences in secondary outcomes were observed between patient groups or technology subsets.
- Major periprocedural complication rate was 2.8%.
Conclusions:
- AF ablation in a low-volume center achieved complication and recurrence-free rates comparable to high-volume centers at one year.
- First AF catheter ablation is feasible in low-volume settings with comparable efficacy and safety using current technologies.
- Further long-term follow-up is warranted.
Background:
Catheter ablation is increasingly being performed worldwide for atrial fibrillation (AF). However, there are concerns of lower success rates and higher complications of AF ablations performed in low-volume centers. Thus, we sought to evaluate the safety and efficacy of AF catheter ablation in a low-volume center using contemporary technologies.
Methods And Results:
71 consecutive patients (50 paroxysmal AF [pAF] vs 21 persistent AF) who underwent first catheter ablation were studied. Primary outcome was AF recurrence rate. Secondary outcomes included periprocedural complications, hospitalization for symptomatic tachy-arrhythmias post-ablation and number of repeat ablations. Mean age of our cohort was 59.1 ± 9.7 years, of which 56 (78.9%) were males. 1-year AF recurrence was 19.5% in pAF and 23.8% in persistent AF (p = 0.694). Ablation in persistent AF group required longer procedural (197.76 ± 48.60 min [pAF] vs 238.67 ± 70.50 min [persistent AF], p = 0.006) and ablation duration (35.08 ± 15.84 min [pAF] vs 52.65 ± 28.46 min [persistent AF], p = 0.001). There were no significant differences in secondary outcomes. Major periprocedural complication rate was 2.8%.Subset analysis on (i) cryoablation vs radiofrequency, (ii) Ensite vs CARTO navigational system and (iii) circular vs high density mapping catheter did not yield significant differences in primary or secondary outcomes.
Conclusions:
The AF ablation complication and recurrence free rates in both paroxysmal and persistent AF at one year were comparable to high-volume centers. Long-term follow up is needed. In addition, first AF catheter ablation in a low-volume center is realistic with comparable efficacy and safety outcomes to high-volume centers using contemporary ablation technologies.
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