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Endoclip papillaplasty restores sphincter of Oddi function: Pilot study
Xiue Yan1, Wei Zheng1, Yaopeng Zhang1
1The Department of Gastroenterology and Hepatology, Peking University Third Hospital, Beijing, China.
Summary
Endoclip papillaplasty may restore sphincter of Oddi function after large endoscopic sphincterotomy. This technique shows promise in preventing recurrent biliary stones and cholangitis.
Area of Science:
- Gastroenterology
- Endoscopic interventions
- Biliary tract physiology
Background:
- Endoscopic sphincterotomy (EST) can impair sphincter of Oddi (SO) function.
- Restoring SO function is crucial for preventing biliary complications.
Purpose of the Study:
- To evaluate the feasibility and efficacy of endoclip papillaplasty.
- To assess the impact of endoclip papillaplasty on SO function restoration.
Main Methods:
- Prospective pilot study of 30 patients with large choledocholithiasis (≥10 mm).
- Patients underwent large-EST followed by endoclip papillaplasty.
- Sphincter of Oddi manometry was performed post-procedure.
Main Results:
- 80% of patients achieved SO basal pressure >10 mmHg post-procedure.
- Manometric parameters of SO function recovered significantly (P>0.05).
- Low rates of mild pancreatitis (20%) and bile duct stone recurrence (3.3%) observed.
Conclusions:
- Endoclip papillaplasty appears feasible for restoring SO function.
- The technique may prevent recurrence of biliary stones and cholangitis.
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