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Updated: Dec 2, 2025

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation
Published on: October 20, 2016
Speckle tracking stress echocardiography: A valuable diagnostic technique or a burden for everyday practice?
Giulia Elena Mandoli1, Maria Concetta Pastore1, Kristina Vasilijevaite2
1Division of Cardiology, Department of Medical Biotechnologies, University of Siena, Siena, Italy.
Insights
Integrating speckle tracking imaging with stress echocardiography shows promise for early coronary artery disease (CAD) detection and myocardial viability (MV) assessment. This advanced technique may improve diagnostic accuracy beyond traditional methods for chronic coronary syndromes (CCS).
Area of Science:
- Cardiology
- Medical Imaging
- Diagnostic Techniques
Background:
- Early diagnosis of coronary artery disease (CAD) is crucial for reducing cardiac mortality.
- Current guidelines recommend functional imaging over electrocardiogram for detecting myocardial ischemia and assessing myocardial viability (MV).
- Stress echocardiography is accessible but has limitations in diagnosing subtle CAD, small lesions, or microvascular angina.
Purpose of the Study:
- To review the potential benefits of combining speckle tracking imaging with stress echocardiography.
- To evaluate the suitability of this combined approach for early myocardial ischemia detection and MV assessment in various clinical scenarios.
- To assess its potential role in managing chronic coronary syndromes (CCS).
Main Methods:
- Review of existing evidence on the integration of speckle tracking imaging and stress echocardiography.
- Analysis of diagnostic accuracy and clinical utility in different patient populations and CAD presentations.
- Comparison with current standard diagnostic approaches for CAD.
Main Results:
- Speckle tracking imaging integrated with stress echocardiography demonstrates promising results in enhancing diagnostic accuracy.
- This combination may offer a more sensitive approach for detecting subtle myocardial ischemia and evaluating MV.
- Despite promising findings, its use is not yet included in current CCS guidelines.
Conclusions:
- Combining speckle tracking imaging with stress echocardiography holds significant potential for improving early CAD detection and MV assessment.
- Further research and clinical validation are needed to establish its role in routine practice and guideline recommendations.
- This integrated technique could offer a valuable, sensitive, and accessible tool for cardiologists.
Abstract:
Non-invasive screening for early diagnosis of coronary artery disease (CAD) represents a key element in the never-ending challenge to reduce cardiac death. Stress/rest electrocardiogram often lacks diagnostic accuracy, especially in asymptomatic patients, in fact the latest guidelines for the diagnosis and management of chronic coronary syndromes (CCS) stated the superiority of functional imaging techniques for the detection of subtle myocardial ischemia and the evaluation of myocardial viability (MV). Stress echocardiography is the most accessible and inexpensive imaging method for the study of CAD, either with pharmacological or with exercise provocative stress, based on visual wall-motion assessment. However, in some cases, such as small coronary lesions or microvascular angina, it loses its diagnostic power, therefore requiring a more sensitive approach. Accordingly, in the last years many authors investigated the possible additive value provided by the integration of an advanced but easy-to-obtain technique, that is speckle tracking imaging, to stress echocardiography, reaching promising results; nevertheless, its use is not included in the latest recommendations for CCS. The present review discusses the potential benefits from using a combination of speckle tracking and stress echocardiography for the early detection of myocardial ischemia and the assessment of MV and its suitability in different clinical scenarios, basing on the available evidence.
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