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Maternal Gestational Diabetes and Early Childhood Obesity: A Retrospective Cohort Study

Cüneyt Ardıç1, Sabri Çolak2, Kerem Uzun1

  • 1Department of Family Medicine, Faculty of Medicine, Recep Tayyip Erdogan University, Rize, Turkey.

Childhood Obesity (Print)
|November 4, 2020
PubMed

Insights

Maternal gestational diabetes mellitus (GDM) significantly increases the risk of childhood obesity. Early identification and intervention for GDM are crucial to prevent obesity in young children.

Area of Science:

  • Public Health
  • Pediatrics
  • Endocrinology

Background:

  • Childhood obesity is a global public health crisis.
  • Gestational diabetes mellitus (GDM) is a known risk factor for offspring overweight and obesity.
  • Understanding the specific risks associated with GDM in early childhood is critical.

Purpose of the Study:

  • To investigate the association between maternal GDM and childhood obesity in children aged 1-3 years.
  • To quantify the risk of developing obesity in children born to mothers with GDM.
  • To inform targeted public health interventions.

Main Methods:

  • Retrospective cohort study including 237 GDM and 296 non-GDM mothers and their children.
  • Maternal GDM diagnosed using World Health Organization (WHO) criteria.
  • Logistic regression models adjusted for confounders (maternal and child factors) and BMI percentile tables used.

Main Results:

  • Maternal GDM was associated with a significantly increased risk of childhood overweight and obesity.
  • Adjusted odds ratios were 2.99 (95% CI 1.14-7.94) for overweight at 2 years and 7.77 (95% CI 1.92-31.37) for obesity at 3 years.
  • Confounding factors including maternal age, BMI, and gestational weight gain were accounted for.

Conclusions:

  • Maternal GDM is a significant risk factor for early childhood obesity.
  • This highlights the need for specific interventions for pregnant women with GDM and their children.
  • Early monitoring and management strategies are essential for this high-risk population.

Keywords:
childhood obesitychildhood risk factorsgestational diabetes mellitus

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